Newest episodes

In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents.

In this conversation, a16z Partner Joel de la Garza sits down with Keycard Cofounder and CEO Ian Livingstone to discuss the continuum from copilots to agents, the security realities of tool-calling, why enterprises will adopt before consumers, and how to control your agents.

Follow Joel on LinkedIn: https://www.linkedin.com/in/3448827723723234/

Follow Ian on X: https://x.com/ianlivingstone

Follow Keycard on X: https://x.com/keycardlabs

Learn more about Keycard: https://www.keycard.sh/

Stay Updated:

Find a16z on X

Find a16z on LinkedIn

Listen to the a16z Show on Spotify

Listen to the a16z Show on Apple Podcasts

Follow our host: https://twitter.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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Most of us want our lives to feel calmer, clearer and more aligned. Yet so often, we hesitate, overthink or delay the changes we know would help us feel better.

This week’s guest believes that what holds us back is not a lack of motivation or confidence, but a lack of self-trust, which is the foundation that shapes everything from our habits to our relationships.

This week on, I’m joined by Dr Shadé Zahrai. Shadé is a behavioural researcher, award-winning peak performance educator and leading authority on confidence and self-doubt. In her new book, Big Trust: Rewire Self-Doubt, Find Your Confidence and Fuel Success, her message is simple:
we need to stop getting in our own way, loosen the grip of self-doubt and learn how to back ourselves when it counts.

Many of Shadé’s insights are shaped by her own journey. After years in corporate roles that were filled with intense self-doubt and even physical anxiety, she found herself starting again when the pandemic hit and her work fell away overnight. Creating simple videos from home to support others became an unexpected turning point – and ultimately the foundation of the work she does today.

During our conversation, we discuss:

• Why self-trust sits at the heart of confidence, action and meaningful change, and how waiting to ‘feel ready’ keeps so many of us stuck.
• The four key attributes that make up self-trust, how our identity shapes our behaviour and why small daily choices become meaningful “proof points” of who we want to become.
• Why confidence doesn’t come first, and why self-trust, not motivation, is what allows us to take action.
• How repeatedly breaking promises to ourselves erodes our identity, and why keeping small commitments rebuilds a sense of capability and worth.
• The powerful connection between our inner narrative and our wellbeing, and how shifting our story changes the way we experience life.

Shadé believes that we are not defined by our doubts but by the choices we make when doubt appears. This episode offers a compassionate, practical guide to strengthening the trust we place in ourselves and invites us to stop outsourcing our worth to external validation. Only then can we reconnect with our core values and begin living from a place of clarity and courage.

I hope you enjoy listening.

Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.

Thanks to our sponsors:

https://www.vivobarefoot.com/livemore

https://drinkag1.com/livemore

Show notes https://drchatterjee.com/608

DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

One Yale economist certainly thinks so. But even if he’s right, are economists any better? We find out, in this update of a 2022 episode.

• SOURCES:
  • James Choi, professor of finance at the Yale School of Management.
  • Morgan Housel, personal finance author and partner at the Collaborative Fund.

• RESOURCES:
  • The Art of Spending Money: Simple Choices for a Richer Life, by Morgan Housel (2025).
  • “Popular Personal Financial Advice versus the Professors,” by James J. Choi (Journal of Economic Perspectives, 2022).
  • “Media Persuasion and Consumption: Evidence from the Dave Ramsey Show,” by Felix Chopra (SSRN, 2021).
  • The Psychology of Money: Timeless Lessons on Wealth, Greed, and Happiness, by Morgan Housel (2020).
  • “In Bogle Family, It’s Either Passive or Aggressive,” by Liam Pleven (Wall Street Journal, 2013).

• EXTRAS: 
  • “Harold Pollack on Why Managing Your Money Is as Easy as Taking Out the Garbage,” by People I (Mostly) Admire (2021).
  • “People Aren’t Dumb. The World Is Hard,” by Freakonomics Radio (2018).
  • “Everything You Always Wanted to Know About Money (But Were Afraid to Ask),” by Freakonomics Radio (2017).
  • “The Stupidest Thing You Can Do With Your Money,” by Freakonomics Radio (2017).

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What if success depends less on merit and more on the quiet transfer of status? In this episode, Guy Kawasaki interviews Toby Stuart, UC Berkeley Haas professor and leading expert on innovation and social networks, to break open the unseen systems that shape who rises and why.

Drawing from his new book Anointed, Toby explains how institutions — universities, investors, employers — confer credibility in ways that compound over a lifetime. He and Guy explore Silicon Valley myths, reverse anointment, and why AI may both democratize and distort fairness.

A sharp, eye-opening look at achievement, status, and the stories we tell ourselves about merit.

—

Guy Kawasaki is on a mission to make you remarkable. His Remarkable People podcast features interviews with remarkable people such as Jane Goodall, Marc Benioff, Woz, Kristi Yamaguchi, and Bob Cialdini. Every episode will make you more remarkable.

With his decades of experience in Silicon Valley as a Venture Capitalist and advisor to the top entrepreneurs in the world, Guy’s questions come from a place of curiosity and passion for technology, start-ups, entrepreneurship, and marketing. If you love society and culture, documentaries, and business podcasts, take a second to follow Remarkable People.

Listeners of the Remarkable People podcast will learn from some of the most successful people in the world with practical tips and inspiring stories that will help you be more remarkable.

Episodes of Remarkable People organized by topic: https://bit.ly/rptopology

Listen to Remarkable People here: **https://podcasts.apple.com/us/podcast/guy-kawasakis-remarkable-people/id1483081827**

Like this show? Please leave us a review — even one sentence helps! Consider including your Twitter handle so we can thank you personally!

Thank you for your support; it helps the show!

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Huberman Lab Essentials episode, I discuss how to optimize your workspace to maximize productivity, focus and creativity.

I explain how key environmental factors such as lighting, the physical layout of your work area and desk setup can influence attention and performance. I also discuss how specific types of sounds can enhance focus and how to adjust your work environment for particular tasks. These practical, flexible protocols can be applied whether you are working from home, in an office or on the road.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Eight Sleep: https://eightsleep.com/huberman

ROKA: https://roka.com/huberman

Timestamps

(00:00:00) Workplace Optimization for Performance

(00:00:36) Clutter, Variables for Workspace Optimization

(00:02:41) Vision & Light, Tool: Mornings & Bright Light; Windows

(00:04:45) Afternoon, Evenings & Light; Tool: Dimming Lights

(00:07:13) Sponsor: Eight Sleep

(00:07:13) Alertness & Visual Focus, Tool: Screen Placement

(00:10:23) Vergence Eye Movement & Alertness, Tool: Visual Breaks

(00:13:08) Cathedral Effect, Creative vs Analytical Thinking, Tool: Ceiling Height by Task

(00:16:08) Sponsor: AG1

(00:16:08) Background Noise to Avoid; White Noise, Pink Noise

(00:20:41) Sound Patterns to Improve Concentration

(00:24:00) Tool: Binaural Beat Frequency for Focus; Dopamine

(00:25:33) Tool: Managing Interruptions

(00:25:29) Sponsor: ROKA

(00:26:57) Sit or Stand for Work?, Tool: Sit-Stand Desk

(00:30:45) Key Takeaways, Flexibility & Changing Locations

Disclaimer & Disclosures

Learn more about your ad choices. Visit megaphone.fm/adchoices

Joel David Hamkins is a mathematician and philosopher specializing in set theory, the foundations of mathematics, and the nature of infinity, and he’s the #1 highest-rated user on MathOverflow. He is also the author of several books, including Proof and the Art of Mathematics and Lectures on the Philosophy of Mathematics. And he has a great blog called Infinitely More.
Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep488-sc
See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc.

Transcript:
https://lexfridman.com/joel-david-hamkins-transcript

CONTACT LEX:
Feedback – give feedback to Lex: https://lexfridman.com/survey
AMA – submit questions, videos or call-in: https://lexfridman.com/ama
Hiring – join our team: https://lexfridman.com/hiring
Other – other ways to get in touch: https://lexfridman.com/contact

EPISODE LINKS:
Joel’s X: https://x.com/JDHamkins
Joel’s Website: https://jdh.hamkins.org
Joel’s Substack: https://www.infinitelymore.xyz
Joel’s MathOverflow: https://mathoverflow.net/users/1946/joel-david-hamkins
Joel’s Papers: https://jdh.hamkins.org/publications
Joel’s Books:
Lectures on the Philosophy of Mathematics: https://amzn.to/3MThaAt
Proof and the Art of Mathematics: https://amzn.to/3YACc9A

SPONSORS:
To support this podcast, check out our sponsors & get discounts:
Perplexity: AI-powered answer engine.
Go to https://www.perplexity.ai/
Fin: AI agent for customer service.
Go to https://fin.ai/lex
Miro: Online collaborative whiteboard platform.
Go to https://miro.com/
CodeRabbit: AI-powered code reviews.
Go to https://coderabbit.ai/lex
Chevron: Reliable energy for data centers.
Go to https://chevron.com/power
Shopify: Sell stuff online.
Go to https://shopify.com/lex
LMNT: Zero-sugar electrolyte drink mix.
Go to https://drinkLMNT.com/lex
MasterClass: Online classes from world-class experts.
Go to https://masterclass.com/lexpod

OUTLINE:
(00:00) – Introduction
(01:58) – Sponsors, Comments, and Reflections
(15:40) – Infinity & paradoxes
(1:02:50) – Russell’s paradox
(1:15:57) – Gödel’s incompleteness theorems
(1:33:28) – Truth vs proof
(1:44:52) – The Halting Problem
(2:00:45) – Does infinity exist?
(2:18:19) – MathOverflow
(2:22:12) – The Continuum Hypothesis
(2:31:58) – Hardest problems in mathematics
(2:41:25) – Mathematical multiverse
(3:00:18) – Surreal numbers
(3:10:55) – Conway’s Game of Life
(3:13:11) – Computability theory
(3:23:04) – P vs NP
(3:26:21) – Greatest mathematicians in history
(3:40:05) – Infinite chess
(3:58:24) – Most beautiful idea in mathematics

Get the free Side Hustle Ideas Database 👉 https://clickhubspot.com/rve

Episode 782: Sam Parr (⁠https://x.com/theSamParr⁠ ) and Shaan Puri (⁠https://x.com/ShaanVP⁠ ) answer listener questions. 

Show Notes:

(0:00) Biggest mistake in business you’ve never talked about

(7:33) Best company to work at to become a millionaire

(20:43) How much revenue did Hampton make in 2025?

(21:28) 2026 misogi’s

(29:46) what’s your f u money purchase

(35:28) what are the mfm OGs up to?

(43:07) how to build compounding wealth

(50:09) Who would be your jail call?

(1:04:41) best idea you’ve heard on the pod

—

Check Out Shaan’s Stuff:

• Shaan’s weekly email – https://www.shaanpuri.com 

• Visit https://www.somewhere.com/mfm to hire worldwide talent like Shaan and get $500 off for being an MFM listener. Hire developers, assistants, marketing pros, sales teams and more for 80% less than US equivalents.

• Mercury – Need a bank for your company? Go check out Mercury (mercury.com). Shaan uses it for all of his companies!

Mercury is a financial technology company, not an FDIC-insured bank. Banking services provided by Choice Financial Group, Column, N.A., and Evolve Bank & Trust, Members FDIC

—

Check Out Sam’s Stuff:

• Hampton – https://www.joinhampton.com/

• Ideation Bootcamp – https://www.ideationbootcamp.co/

• Copy That – https://copythat.com

• Hampton Wealth Survey – https://joinhampton.com/wealth

• Sam’s List – http://samslist.co/

My First Million is a HubSpot Original Podcast // Brought to you by HubSpot Media // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano //

The Afro is one of the most iconic hairstyles of the last century. And one of its main ingredients was a hair product – Afro Sheen. But Afro Sheen did so much more than make Black afros shine. It was the money behind the television show Soul Train, it helped fuel the civil rights movement – all because of an entrepreneur named George Johnson. 

For decades, Joan and George Johnson owned and ran Johnson Products Company, a Black hair care company out of Chicago. Their intimate understanding of what Black people wanted and needed – for their hair and for their lives –  helped grow the Black middle class and became an engine for Black culture and power. They helped turn the Black haircare industry into what is now a multi-billion-dollar industry. But although they helped create this industry, they no longer have a part in it. 

Today on the show – the story of the rise and fall of Johnson Products. We’re gonna tell you this story in three hairstyles. The conk, the afro… and the jheri curl. 

Related episodes:

This Ad’s For You

‘Soul Train’ and the business of Black joy

Fashion Fair’s makeover

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This episode of Planet Money was hosted by Sonari Glinton and Erika Beras. It was produced by James Sneed, edited by Marianne McCune, fact-checked by Sierra Juarez, and engineered by Jimmy Keeley. Alex Goldmark is Planet Money’s executive producer.

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If we’re truly in an AI bubble close to bursting, how do we avoid economic catastrophe? That’s a question we bring to Andrew Ross Sorkin this week, whose new book, 1929: The Inside Story of The Greatest Crash in Wall Street History, has as much to say about the present as it does the past. We ask Andrew what warning signs he sees in the market, how the government should respond to a crash, and what lessons from the 1920s apply today.

Learn more about your ad choices. Visit podcastchoices.com/adchoices

No.1 Health Doctor Benjamin Bikman breaks down keto, insulin resistance, sugar addiction, and calorie counting, and the ONE test that predicts weight gain!

Dr Benjamin Bikman is a metabolic scientist and researcher focused on the link between insulin resistance and chronic disease. He is Professor of Cell Biology at Brigham Young University and Co-founder of Insulin IQ. 

Follow Dr Benjamin:

Instagram – https://bit.ly/3MGLKNH

X – https://bit.ly/3N6hziZ 

Website – https://bit.ly/491iGI6 

He explains:

◼️Why shrinking fat cells depends on lowering insulin, not eating less

◼️How ketones act as a brain fuel that kills hunger and boosts metabolism

◼️Why constant carb intake traps energy and makes willpower fail

◼️How GLP-1 drugs may worsen muscle loss and long-term metabolic health

◼️Why a fasting insulin test reveals problems years before diabetes

[00:00] What Should People Focus on for 2026 When It Comes to Diet?
[02:32] What Is Metabolism?
[07:18] Why Calorie Counting Doesn’t Work
[09:57] Ketones and Fat Loss
[22:37] How the Liver Decides What to Do With Fat
[25:09] Is Keto Sustainable?
[27:15] Could Keto Help With Eating Disorders and Sugar Addiction?
[30:24] The Effects of Keto on the Heart
[32:54] Should You Take Exogenous Ketones?
[38:04] Is Keto Suitable for Women?
[44:36] The Perfect Diet and Lifestyle for 2026
[51:12] Steve’s Ketone Levels After a Keto Shot
[57:04] Ads
[58:40] Continuing the Perfect Lifestyle for 2026
[59:42] When Not to Do Keto
[01:05:48] How Cancers Use Sugar for Energy
[01:10:36] Are Vitamins and Supplements Contributing to Obesity?
[01:21:19] Thoughts on Ozempic and GLP-1s
[01:26:05] Ads
[01:32:58] What’s the Best Sweetener to Use?
[01:34:57] Collagen Peptides
[01:37:03] Creatine
[01:38:06] How to Get Rid of Stubborn Fat for Good
[01:45:23] How Stress Contributes to Weight Gain
[01:49:31] Check Your Testosterone Levels
[01:51:39] What Tests Can We Do at Home?
[01:52:49] If You Could Have One Thing for Life, What Would It Be?

The Diary Of A CEO:

◼️Join DOAC circle here – https://doaccircle.com/ 

◼️Buy The Diary Of A CEO book here – https://smarturl.it/DOACbook 

◼️The 1% Diary is back – limited time only: https://bit.ly/3YFbJbt 

◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb 

◼️Get email updates – https://bit.ly/diary-of-a-ceo-yt 

◼️Follow Steven – https://g2ul0.app.link/gnGqL4IsKKb 

Independent research: https://benjmainbikman2.tiiny.co

Sponsors:

Pipedrive – https://pipedrive.com/CEO
Wispr – Get 14 days of Wispr Flow for free at https://wisprflow.ai/DOAC
Ketone – https://ketone.com/STEVEN for 30% off your subscription order

It’s not always the most wonderful time of the year.

Every December, we’re told to be merry and stay positive. But a lot of us don’t feel that way. And when we don’t, the pressure to be happy makes everything worse. Sadness feels like failure. Grief feels like a personal mistake. Depression becomes something to hide.

But what if dark moods aren’t problems to fix? What if they’re part of being human?

Today’s guest is philosopher Mariana Alessandri, author of Night Vision, a book about how to honor the emotions we usually try to outrun. It’s not a celebration of sadness, but Alessandri calls bullshit on the culture of toxic positivity and the idea that happiness is something we’re supposed to choose on command.

Sean and Mariana talk about why Americans are addicted to the light, why “cheering people up” often backfires, how Stoicism shaped our emotional habits, and what it looks like to sit with grief instead of shaming ourselves for feeling it.

Host: Sean Illing (@SeanIlling)

Guest: Mariana Alessandri (@mariana.alessandri), associate professor of philosophy at the University of Texas-Rio Grande Valley and author of Night Vision: Seeing Ourselves Through Dark Moods.

We would love to hear from you. To tell us what you thought of this episode, email us at thegrayarea@vox.com or leave us a voicemail at 1-800-214-5749. Your comments and questions help us make a better show.

And you can watch new episodes of The Gray Area on YouTube.

Listen to The Gray Area ad-free by becoming a Vox Member: vox.com/members. This holiday season, your membership goes further: when you join Vox as an annual Member, we’ll gift a free membership to a reader who can’t afford it. By joining today, you’ll get 30% off for an annual membership, and we’ll match your membership. And if you can’t afford it, visit that same link to apply for a free membership through our gift program.

Learn more about your ad choices. Visit podcastchoices.com/adchoices

Get our AI Video Guide: https://clickhubspot.com/rhj

Episode 91: How far has AI video really come—and what happens when your digital self can work, teach, or sell for you? Matt Wolfe (https://x.com/mreflow) and Maria Gharib (https://uk.linkedin.com/in/maria-gharib-091779b9) sit down with Victor Riparbelli (https://x.com/vriparbelli), CEO and co-founder of Synthesia, the company leading the charge in AI-generated avatars that can communicate in over 140 languages.

Victor’s background includes pioneering research in AI video, growing Synthesia since 2017 to become an industry leader in lifelike, customizable avatars used for everything from business training to personalized marketing at scale.

This episode dives deep into what the rise of AI video agents means for the business world, what it takes to create realistic digital avatars (hint: it’s all about the body language), and how lowering the cost and complexity of video creation is changing internal communication and customer engagement. Plus, hear Synthesia’s ethical approach to deepfakes, licensing data, and critical business use cases that work right now (and not just as novelty). If you’ve ever wondered how close we are to having your AI twin closing deals or teaching your kids, this is the one to check out.

Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd

—

Show Notes:

• (00:00) AI Avatar and Future Video

• (03:54) AI-Driven Interactive Video Evolution

• (07:45) Corporate Shift to Video Communication

• (11:42) AI Improving Digital Human Realism

• (13:12) Accent Preservation in Voice Technology

• (16:41) Video to Replace PowerPoints

• (20:11) Balancing Content Moderation Challenges

• (22:50) Regulating AI Outputs, Not Inputs

• (26:36) Conversational Learning Revolution

• (29:56) Future of AI-Powered Video Creation

—

Mentions:

• Victor Riparbelli: https://www.linkedin.com/in/victorriparbelli/

• Synthesia: https://www.synthesia.io/

• Victor’s Ted Talk: https://www.youtube.com/watch?v=6wCml0g2mRE

• Shutterstock: https://www.shutterstock.com/

• Google Translate: https://translate.google.com/

• Runway ML: https://runwayml.com/

• Kling: https://openart.ai/video/i2v/kling2.1

• Veo: https://v03ai.com/home

• Sora: https://www.sora-2.studio/

Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw

—

Check Out Matt’s Stuff:

• Future Tools – https://futuretools.beehiiv.com/

• Blog – https://www.mattwolfe.com/

• YouTube- https://www.youtube.com/@mreflow

—

Check Out Nathan’s Stuff:

• Newsletter: https://news.lore.com/

• Blog – https://lore.com/

The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

Ian Bremmer, president and founder of Eurasia Group, joins Jessica Tarlov, co-host of The Five and Raging Moderates, to unpack the biggest risks facing the world in 2026 — from Trump’s political revolution and U.S. intervention abroad to Europe’s instability, AI, and the global energy race.

Follow Ian, @ianbremmer. Follow Jessica, @jessicatarlov.

Learn more about your ad choices. Visit podcastchoices.com/adchoices

Google’s market share is shrinking, customer behavior is shifting, and as business owners, we’ve got to adapt.

The good news is people still need your help. It’s just how they find you that’s changing.

By the end of this episode, you’re going to have a proven roadmap for how to get found in ChatGPT and other AI tools.

Return guest Tanya Van Gastel (Episode 700) from RankingonAI.com is back to pull back the curtain on how you can get ChatGPT to recommend your business.

Tune in to Episode 717 of the Side Hustle Show to learn:

• The three foundational things every business should do to improve AI visibility
• How to create content that actually gets cited
• The biggest content mistake people make

Full Show Notes:How to Get ChatGPT to Recommend Your Business

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About The Side Hustle Show

This is the entrepreneurship podcast you can actually apply!

The award-winning small business show covers the best side hustles and ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠side hustle ideas⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. We share how to start a business and ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠make money online⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and offline, including online business, side gigs, freelancing, marketing, sales funnels, investing, and much more.

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Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.

This episode is brought to you by:

• Gusto simple and easy payroll, HR, and benefits platform used by 400,000+ businesses: https://gusto.com/tim 
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• Coyote the card game​, which I co-created with Exploding Kittens: https://coyotegame.com

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Timestamps:

• [00:00:00] Who is Dominic D’Agostino?
• [00:04:37] Ketosis benefits: Quieting the mind, GABA elevation, metabolic psychiatry.
• [00:09:24] My Lyme disease story: Pseudo-dementia reversed in 3-4 days of ketosis.
• [00:13:50] Spirochetes are glycolytic: Starve the bug, boost the immune response.
• [00:19:20] Ketosis and cancer: Slowing glycolytic tumors, enhancing standard care.
• [00:20:50] My 18-day keto experiment: Mood stabilization, Alzheimer’s prevention hopes.
• [00:23:19] Metabolic memory: Carryover effects and Valter Longo’s fasting mimicking research.
• [00:27:11] Intermittent fasting as keto on-ramp: My 2-8 p.m. eating window.
• [00:29:15] Dom’s budget keto meal: Canned mackerel, MCT oil, apple cider vinegar.
• [00:33:28] My ketone measurement paradox: Feeling sharp at 0.2 mM readings.
• [00:36:56] The carburetor analogy: Ketone production vs. utilization explained.
• [00:38:43] Breath ketones vs. blood ketones: Better indicator in caloric deficit.
• [00:39:47] Gluconeogenesis fears: Fat, fiber, and salt to slow protein absorption.
• [00:45:25] The bunless double cheeseburger question: 80 grams of protein in one sitting.
• [00:49:03] Post-meal walking and GLUT4 activation: Timing your glucose disposal.
• [00:51:02] CGM and ketone monitor limitations: When your devices gaslight you.
• [00:58:05] Rabbit starvation and protein-veggie days: Why your body won’t bankroll its own ketosis.
• [01:05:44] Alzheimer’s prevention: Biomarkers, B12, hsCRP, and metabolic health.
• [01:09:40] My family history: Letrozole, metabolic dysfunction, and rapid cognitive decline.
• [01:13:17] Minimum effective dose: 80% of benefits from low-carb Mediterranean.
• [01:18:56] One week per month protocol: Aggressive calorie cut to ramp ketones.
• [01:23:12] GKI sweet spot: Target 1-4, aim for 1-2 during intensive weeks.
• [01:36:22] Exogenous ketones 101: Palatability, tolerability, pharmacokinetics, toxicity.
• [01:39:21] 1,3-Butanediol warnings: Liver toxicity, NAD depletion, dependency risk.
• [01:54:22] Intermittent fasting vs. ketogenic breakfast.
• [01:59:09] My accidental intoxication story.
• [02:03:23] Dr. Veech tribute: Student of Hans Krebs, ketone ester pioneer.
• [02:05:08] Fiber on keto: Wild blueberries, broccoli, apples, walnuts.
• [02:09:58] The tainted gummies incident: Dom’s forensic investigation underway.
• [02:13:08] Thanks to Dr. Boz and Medifoodz.
• [02:16:19] Parting thoughts.

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