a16z Podcast

  • Marc Andreessen on the Mindset of Great Founders — with David Senra

    Marc Andreessen joins David Senra for a conversation about entrepreneurship, history, and what drives some of the world’s most ambitious builders. In this conversation with David, Marc reflects on patterns he’s seen across great founders,…

  • Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

    This conversation with Emil Michael, undersecretary of defense for research and engineering and acting director of the Defense Innovation Unit, was recorded at the a16z American Dynamism Summit in Washington, D.C. Michael walks through how…

  • Palantir CEO Alex Karp on the Zero-Sum AI Race

    This conversation with Alex Karp, cofounder and CEO of Palantir, was recorded at the a16z American Dynamism Summit in Washington, D.C. Karp discusses the role of technology in modern warfare, Silicon Valley’s obligations to national…

  • What It Takes to Clear a Million Crimes a Year with Flock Safety’s CEO

    In this episode, previously aired on Cheeky Pint, Garrett Langley describes how a stolen gun in his Atlanta neighborhood led him to build Flock Safety, now deployed in more than 6,000 cities and involved in…

  • The Top 100 Gen AI Consumer Apps

    Anish Acharya speaks with Olivia Moore about the latest edition of the a16z Top 100 AI Apps report. They cover why ChatGPT is still 30 times bigger than Claude on web, how the three major…

  • Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

    Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide…

  • Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

    Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risks, and how…

  • Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

    In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay “Anthropic and Alignment” and the broader collision between AI power and state power…

  • Ambience CEO Nikhil Buduma on AI in Clinical Workflows

    a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why Ambience started by…

  • Ben Horowitz On What Makes a Great Founder

    On the show Long Strange Trip, Sequoia Capital partner Brian Halligan speaks with a16z’s Ben Horowitz about what separates great founder CEOs from everyone else. Ben explains why first-time founders lose confidence, defer too much…

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