a16z Podcast

  • Dylan Patel on the AI Chip Race – NVIDIA, Intel & the US Government vs. China

    Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip…


  • Charlie Kirk and the Rise of Political Violence

    In this episode of Honestly with Bari Weiss, we share a special conversation featuring a16z general partner Katherine Boyle in the wake of Charlie Kirk’s shocking assassination. Katherine reflects on what courage means in a…


  • The Death of Search: How Shopping Will Work In The Age of AI

    The web is unhealthy, and AI agents are about to rewrite how we shop. In this episode, a16z General Partner Alex Rampell and Partner Justine Moore explore how AI agents will change commerce and the…


  • How OpenAI Built Its Coding Agent

    OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software? In this episode, General Partner…


  • Faster Science, Better Drugs

    Can we make science as fast as software?  In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, which uses foundation…


  • Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy

    In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, and how to…


  • Inside the $13T Mortgage Machine

    The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software.  In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend), Mike Yu (co-founder…


  • Chris Dixon on How to Build Networks, Movements, and AI-Native Products

    Why do some consumer products explode into networks that reshape the internet, while others fade away? Today on the podcast, a16z general partners Anish Acharya and Chris Dixon take on that question. Anish invests in…


  • Mark Cuban on Sports, Healthcare, and Social Media

    What happens when AI collides with salesmanship, streaming-era sports, and healthcare? In this episode, Erik Torenberg is joined by Mark Cuban, entrepreneur, Dallas Mavericks co-owner, and founder of Cost Plus Drugs. Topics include fiery group…


  • The Little Tech Agenda for AI

    Who’s speaking up for startups in Washington, D.C.? In this episode, Matt Perault (Head of AI Policy, a16z) and Colin McCune (Head of Government Affairs, a16z) unpack the “Little Tech Agenda” for AI- why AI…


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