Three leading researchers from the Mount Sinai Health System discuss how ketamine, cannabis, and ecstasy are being used (or studied) to treat everything from severe depression to addiction to PTSD. We discuss the upsides, downsides, and regulatory puzzles.

The families of U.S. troops killed and wounded in Afghanistan are suing several companies that did reconstruction there. Why? These companies, they say, paid the Taliban protection money, which gave them the funding — and opportunity — to attack U.S. soldiers instead. A look at the messy, complicated, and heart-breaking tradeoffs of conflict-zone economies.

The dean of Yale’s School of Management grew up in a small village in Guyana. During his unlikely journey, he has researched video-gaming habits, communicable disease, and why so many African-Americans haven’t had the kind of success he’s had. Steve Levitt talks to Charles about his parents’ encouragement, his love of Sports Illustrated, and how he talks to his American-born kids about the complicated history of Blackness in America.

Trump says it would destroy us. Biden needs the voters who support it (especially the Bernie voters). The majority of millennials would like it to replace capitalism. But what is “it”? We bring in the economists to sort things out and tell us what the U.S. can learn from the good (and bad) experiences of other (supposedly) socialist countries.

Netflix co-founder Reed Hastings came to believe that corporate rules can kill creativity and innovation. In this latest edition of the Freakonomics Radio Book Club, guest host Maria Konnikova talks to Hastings about his new book, No Rules Rules, and why for some companies the greatest risk is taking no risks at all.

Thanks to daily Covid testing and regimented protocols, the new football season is underway. Meanwhile, most teachers, students, and parents are essentially waiting for the storm to pass. And school isn’t even a contact sport (usually).

She’s best known for playing neurobiologist Amy Farrah Fowler on The Big Bang Theory, but the award-winning actress has a rich life outside of her acting career, as a teacher, mother — and a real-life neuroscientist. Steve Levitt tries to learn more about this one-time academic and Hollywood non-conformist, who is both very similar to him and also quite his opposite.

We all know our political system is “broken” — but what if that’s not true? Some say the Republicans and Democrats constitute a wildly successful industry that has colluded to kill off competition, stifle reform, and drive the country apart. So what are you going to do about it?

We explore the science, scalability, and (of course) economics surrounding the global vaccine race. Guests include the chief medical officer of the first U.S. firm to go to Phase 3 trials with a vaccine candidate; a former F.D.A. commissioner who’s been warning of a pandemic for years; and an economist who thinks Covid-19 may finally change how diseases are cured.

A new interview show with host Steve Levitt. Today he speaks with the Harvard psychologist and linguist Steven Pinker. By cataloging the steady march of human progress, the self-declared “polite Canadian” has managed to enrage people on opposite ends of the political spectrum. Levitt tries to understand why.