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Megan O’Connor is the co-founder and CEO of Nth Cycle. Megan’s problem is this: How do you create a new system that can both refine the raw metals ...

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AI is better than humans at a lot of things, but physical tasks – even seemingly simple ones like folding a shirt – routinely stump AI-powered ...

Jacob Glanville is the founder and CEO of Centivax. Jacob’s problem is this: Can you create a vaccine that protects people against almost all strains of ...

Alex Wiltschko got obsessed with perfume when he was 12 years old. He grew up to be an AI researcher at Google. Then he started Osmo, a company that fused his ...

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Nick Jacobson and his team at Dartmouth medical school spent over 100,000 hours trying to build an AI chatbot that can serve as a safe, effective therapist. ...

This week, Nate and Maria discuss AI 2027, a new report from the AI Futures Project that lays out some pretty doom-y scenarios for our near-term AI future. ...

Blake Scholl is the founder and CEO of Boom Supersonic. Blake’s problem is this: Can you build a commercial airplane that flies faster than the speed of ...

Fiorenzo Omenetto is a professor of biomedical engineering at Tufts University and the director of Silklab. Fiorenzo’s problem is this: How do you turn a ...

A few years ago, a ransomware gang called LockBit rose from obscurity to extort over $100 million from organizations around the world. A security strategist ...

Christopher Kirchhoff helped launch a Defense Department office that aimed to bring Silicon Valley technology to the US military.  Christopher’s problem ...