*Or at least, sort of bringing back mammoths and dodos. Beth Shapiro is the chief scientific officer at Colossal Biosciences and the author of How to Clone a ...

The elevator made the modern city possible: No elevators, no skyscrapers. Today, people are working on entirely new kinds of elevators that can go higher and ...

The invention of synthetic fertilizer was one of the key breakthroughs of the 20th century. It’s the reason we can grow enough food to feed billions of people. ...

Jennifer Holmgren is the CEO of LanzaTech. Her problem is this: How do you capture pollution from factories, feed it to bacteria, and get the bacteria to ...

Moving from fossil fuels to renewable energy will require huge amounts of copper, lithium, and other metals. Kurt House is the co-founder and CEO of KoBold ...

Dalial Freitak and Annette Kleiser are the co-founders of Dalan Animal Health, a company that has brought to market the first vaccine for insects. Their ...

Sean Hunt is the co-founder and CTO of Solugen, a company that sells around $100 million a year of industrial chemicals. Sean’s problem is this: How do ...

Refrigeration is an underrated technology. It completely transformed what billions of people eat every day.  Today’s guest, Nicola Twilley, tells the story of ...

As generative AI tools improve, it is becoming easier to digitally manipulate content and harder to tell when it has been tampered with. Today we are talking ...

Aluminum is the most abundant metal in the Earth’s crust. It’s cheap, ubiquitous, and surprisingly energy dense. Peter Godart is the co-founder and CEO of ...

Sarah Rudd is the co-founder and CEO of the soccer analytics company src | ftbl (It’s pronounced “Source Football.”) Sarah’s problem is this: How do you model ...

Jimmy Buffi is the CEO and co-founder of Reboot Motion, which uses biomechanics to help athletes in Major League Baseball and the NBA. Jimmy’s problem is ...

On the next few episodes of What’s Your Problem, Jacob Goldstein is talking with people working at the frontiers of technology to help elite athletes ...

Laura Niklason is the co-founder and CEO of Humacyte. Laura’s problem is this: How can you use human cells to create blood vessels that surgeons can pull ...

As demand for clean energy grows, engineers around the U.S. are working on a new generation of nuclear reactors. These designs reflect how nuclear energy could ...

This week on Risky Business, Nate and Maria discuss whether Supreme Court Justice Sonia Sotomayor should retire, the perils of sports betting among ...

Tim Harford is joined by Jacob Goldstein to answer your questions. Does winning the lottery make you unhappy? Is Bitcoin bad for the economy? When does ...

Palm oil is a cheap and remarkably versatile vegetable oil. It’s in a ton of products, from food to cosmetics, detergent, and chewing gum. But producing so ...

Last year, the FDA approved a treatment for sickle cell disease using a revolutionary new gene editing technology called CRISPR. Rachel Haurwitz conducted ...

Robert Langer has co-founded dozens of companies, holds over a thousand patents, and is a pioneering figure in drug delivery and tissue engineering. Robert has ...