Proteins are molecular machines that must first assemble themselves to function. But how does a protein, which is produced as a linear string of amino acids, ...

The way we deliver healthcare has changed enormously over the last century, shifting from house calls by doctors to your own to institutionalized settings like ...

Primary care was meant to be the front door to the healthcare system, but in some ways never set up for success to begin with. We need a new operating system ...

 We cover the tricky but important topic of Section 230 of the Communications Decency Act. The 1996 law has been in the headlines a lot recently, in the ...

Given recent events around George Floyd and far beyond, this special episode of the a16z Podcast features Shaka Senghor, a leading advocate for criminal ...

For a SaaS company, it’s easier to move upmarket than down, and this gives SaaS startups the advantage against incumbents. In this episode,  David ...

Today’s episode is about a practical application of crypto — namely, the way it can “tokenize” fandom. More broadly, it’s about fan engagement, and the ...

Our understanding of the human brain and its disorders has always been limited by our lack of access to living, human, developing brain tissue. For the first ...

Pandemics are predictable; what’s not predictable is the intensity, or the precise timing of arrival. That’s where early detection — not just ...

This podcast (first recorded in 2019, now being rerun) — is a podcast about podcasting: But it’s really all about audio. A lot’s ...

 In normal times, every company operates against some hypothetical growth model—a data-driven framework that describes how your product grows and how you ...

In this episode of a16z bio Journal Club, general partner Vijay Pande, bio deal team partner Andy Tran, and bio editor Lauren Richardson discuss a novel ...

Video game technology has evolved into a global phenomenon that extends far beyond entertainment. In this episode, John Riccitiello, CEO of the game software ...

In this episode of the a16z Podcast, we take a deep dive into the world of drug development—specifically “undruggable drugs”: a category of ...

This episode—which originally took place as a live event—is a conversation between Seattle Seahawks linebacker Bobby Wagner and a16z Cultural Leadership Fund ...

The Chief Security Officer (CSO/CISO) used to manage on-premise servers, now the information they have to secure has migrated to the cloud. As the ...

a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature — what papers we’re reading, and why they ...

Announcing a16z Journal Club, a new show where we curate and discuss recent research papers with a16z experts and others.  This new show continues the a16z ...

Here is Ali’s tweetstorm on the Narrow Waist of Blockchain Computing 

“It’s Time to Build” by Marc Andreessen.  You can also find and share this essay at a16z.com/build