a16z Podcast

Human nature fears the unknown, and with the rapid progress of AI, concerns naturally arise. Uncanny robocalls, data breaches, and misinformation floods are among the worries. But what about security in the era of large language models? In this episode, we hear from security leaders at OpenAI, Anthropic, and Google DeepMind. Matt Knight, Head of … Read more

In recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models in early 2024. While creative tools often steal the spotlight, AlphaFold 2 marked a groundbreaking AI breakthrough in biology in 2021. Since its release, this pioneering tool … Read more

Over 3,700 companies applied to a16z’s SPEEDRUN. In this episode, we meet the founders pushing the boundaries of what games can be. From the fusion of traditional gaming elements with modern tech-twists, a16z General Partner Andrew Chen and Partner Josh Lu discuss the challenges and wins of creating games that are not only fun but … Read more

Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and why we need to support AI research at all levels — from the classroom to the war room. In this episode, we distinguish science fiction from science reality in the ever-evolving AI … Read more

The gaming industry stands as a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engines, and immersive multiplayer experiences.  In this episode, a16z cofounder Marc Andreessen and Andrew Chen, General Partner at a16z Games, dig into why a16z was compelled to establish a dedicated games fund. They explore the … Read more

From air-defining radar and electronic systems that helped the Allies win World War II, the origins of Silicon Valley are deeply rooted in government and defense. In today’s episode, we get the chance to revisit that relationship with the United States Deputy Secretary of Defense, Kathleen Hicks. Deputy Secretary Hicks has spent decades of her … Read more

From judging inventions on “Shark Tank” to reshaping the image of NBA ownership, Mark Cuban is known for many things. In this chat with a16z General Partner David Ulevitch, he discusses the importance of entrepreneurship for maintaining America’s status as the most innovative place on the planet. This includes making big bets, like he’s doing … Read more

At the a16z LP Summit, we brought hundreds of our limited partners and portfolio founders together in Las Vegas. The event was truly overflowing with stories of how founders are challenging the status quo and harnessing technology to make the world a better place. Amidst these stories, it became clear that in the realms of … Read more

Generative AI has initiated a transformative shift, reshaping our world in unprecedented ways. In a16z’s AI Revolution series, we engage some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. In this episode, General Partner David George chats … Read more