Special Episode: The Trial of Sam Bankman-Fried Sam Bankman-Fried, the former crypto mogul, is on trial for fraud. On today’s show, we talk to Lidia Jean Kott, w […]

Getting Yeast to Make Medicine Christina Smolke is the co-founder and CEO of Antheia. Antheia is a synthetic biology company — they’re in the business of gen […]

Could a Robot Make Your Salad? Stephen Klein is the co-founder and CEO of Hyphen, a company that is developing an automated make line. Stephen’s problem is this: H […]

What the Industrial Revolution Teaches Us About the AI Revolution Simon Johnson is an MIT economist and the co-author of a new book called “Power and Progress: O […]

Can AI Tutors Help Kids Learn? Khan Academy Thinks So Sal Khan is the founder and CEO of Khan Academy. Sal’s problem is this: How do you design an AI that can g […]

Smallpox: Gone but Not Forgotten from Incubation What can we learn from the centuries-long quest to eradicate smallpox, once the scourge of humanity? And how did it […]

Going to the Doctor Sucks. Can AI Make it Better? Allon Bloch is the co-founder and CEO of K Health. Allon’s problem is this: Can you use AI to make seeing a d […]

Spotting Wildfires with AI Sonia Kastner is the founder and CEO of Pano. Sonia’s problem is this: How do you use data and machine learning to mitigate the damage c […]

Is the Era of Free Returns Over? Amit Sharma is the founder and CEO of Narvar. Narvar works with companies such as Sephora, Lululemon and Home Depot to manage the […]

Creative Technology at Pixar Danielle Feinberg is a Visual Effects Supervisor at Pixar Animation Studios. Danielle’s problem is this: How do you optimize t […]

How To Make AI Safer & More Reliable Yaron Singer is the founder and CEO of Robust Intelligence. Yaron’s problem is this: How do you reduce AI’s security and rel […]

Quantum Computers Could Change Everything Chris Monroe is the co-founder and chief scientist of IonQ. Chris’s problem is this: How do you build a quantum c […]

The 2023 Unhedged Stock Draft Seven stocks are powering the market: Alphabet, Amazon, Apple, Meta, Microsoft, Nvidia and Tesla. How will they do in the second half […]

Predicting Human Health with AI Charles Fisher is the co-founder and CEO of Unlearn AI. Charles’ problem is this: How do you build an AI model that can predict h […]

Breastfeeding, Black Market Baby Formula, and Bobbie Laura Modi is the founder and CEO of Bobbie, a company that makes baby formula and sells it directly to parents. […]

Making Immigration Cheaper & Easier Xiao Wang is the founder of a company called Boundless. Xiao’s problem is this: How do you make it cheaper and easier for p […]

The Wind Power Pioneer Still Pushing the Frontier Henrik Stiesdal got his start in wind power back in the 70s. The price of oil had gone way up, and he wanted to […]

The Mystery at the Heart of ChatGPT One of the most amazing things about ChatGPT and other, similar AI models: Nobody really understands what they can do. Not even […]

Scrubbing Carbon from the Air Dan Friedmann is the CEO of Carbon Engineering. The company is at the frontier of a new industry, direct air capture. They just broke […]

Building a Plane to Help Save the World Does flying have to be bad for the environment? Val Miftakhov, the founder and CEO of ZeroAvia, doesn’t think so. His c […]