The Ozempic Expert: Ozempic Transforms Your Gut Microbiome! People Are Being Overdosed On Ozempic! Microdosing Saved My Life! – Dr Tyna Moore

0:00:03 this is not what they’re telling us we can start to heal some of these chronic
0:00:07 lifestyle conditions that are so rampant with tiny doses of this it’s like
0:00:10 opening a window of opportunity for somebody to completely change their
0:00:14 life dr. Tina Moore is a distinguished in naturopathic position whose
0:00:18 groundbreaking work is leading the way in combating some of the biggest diseases
0:00:22 in medical conditions that are modern world currently faces everyone’s
0:00:25 saying that ozepic is evil this is the worst thing ever but a lot of people are
0:00:29 being overdosed for weight loss and this leads to a very high risk for side
0:00:33 effects but ozepic done correctly has all these other benefits that have nothing
0:00:37 to do with weight loss and they are just mind-blowing healing and reversing type
0:00:41 one diabetes Parkinson’s and Alzheimer’s we’ve got studies showing really positive
0:00:45 impacts on depression and anxiety and potentially reducing cancer risk it
0:00:48 shifts your gut microbiome to a more favorable microbiome and then my daughter
0:00:52 PCOS symptoms reverse which is probably one of the number one drivers of
0:00:56 infertility in young women I mean holy and I’ve seen it with my patients and
0:01:01 I’ve seen it with myself cuz I’ve lived with chronic pain my whole life and I
0:01:05 remember by the end of 2021 thinking if this doesn’t get better I think I’m
0:01:10 gonna kill myself but I started myself at a tiny little dose and the
0:01:15 destruction fell away dr. Tina Moore what would you scream to the world right
0:01:20 now we are eating a chemical storm of a food supply young women are bathing in
0:01:23 toxic chemicals through their beauty habits microbiome disruption from all
0:01:27 the antibiotics I joke that humans are going extinct but I think it’s really
0:01:30 happening if we don’t write this ship but there’s things we can do that are
0:01:33 non-negotiable that have nothing to do with drugs you’re six pillars for a
0:01:39 pain-free life yes first of all I would congratulations Diroversea gang we’ve
0:01:43 made some progress 63% of you that listen to this podcast regularly don’t
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0:02:01 bigger the channel gets as you’ve seen the bigger the guests get thank you and
0:02:04 enjoy this episode
0:02:16 dr. Tina Moore who are you by profession and what is the mission that you’re on
0:02:20 so I’m a naturopathic physician and a chiropractor I don’t know if you have
0:02:26 naturopathic physicians here in the UK we are trained formally in a four-year
0:02:30 medical program and we take national board exams North American I should say
0:02:35 and we are taught root cause medicine so the functional medicine community
0:02:39 basically appropriated our medicine many years ago if you’ve heard a functional
0:02:43 you’ve had doctors on their functional medicine practitioners and it’s the idea
0:02:48 that the body can heal itself we are looking to restore homeostasis in the
0:02:51 individual so why are things aright I’m less interested in someone’s diagnosis
0:02:54 as much as I am why are they presenting with that symptom picture what’s going
0:03:00 on and I was mentored up by one of the finest naturopathic physicians in our
0:03:05 profession over the past many decades and he died of cancer in 2013 and I took
0:03:10 over his practice he was a force to be reckoned with so I carry that flag with
0:03:17 me and he was a truth teller and he was often ostracized by our profession for
0:03:21 being ahead of the game and you know being ahead of the story usually and I
0:03:26 learned so much from him about metabolic health and how metabolic health was
0:03:31 really the root cause driver of so many diseases lifestyle induced diseases that
0:03:34 we’re seeing in an on a worldwide level can you give me just a bit of a glimpsing
0:03:39 for someone that’s never heard the term naturopathic physician before which I
0:03:44 guess means naturopathic doctor right what is the difference between like a
0:03:50 normal doctor and a naturopathic doctor so a traditional allopathic physician is
0:03:54 what you’re going to be familiar with with an MD they’re trained in a system
0:03:59 where algorithmically they are taught to find disease processes and then they
0:04:04 have a standard of care that they follow which is to prescribe X Y and Z yeah for
0:04:08 the standard of care and that’s not how they always were naturopathic medicine
0:04:16 was born out of old timey European MDs so back in Germany and you know long
0:04:20 time ago when we didn’t have all the fancy lab tests and we didn’t have all
0:04:26 the fancy pharmaceuticals we were treating people to bolster their health
0:04:30 really you know it’s taking you as an individual finding out what makes you
0:04:34 tick and then how can we optimize your health overall symptoms and illness falls
0:04:39 away when you treat the body when you treat the individual in front of you so
0:04:43 I don’t treat diseases I treat people that’s the difference whereas in
0:04:51 allopathic medicine they are very obsessed with the diagnosis and then
0:04:57 what pills do we apply to that diagnosis which is different than why is this
0:05:02 person presenting this way and what can we do to help them along the journey of
0:05:07 optimizing their health so those symptoms fall away and you said you took over a
0:05:11 clinic there yeah what kind of patients do you see in that practice did you see
0:05:16 in that practice and what was the sort of variety of illness or disorder or
0:05:19 disease that you came across so his practice was predominantly muscular
0:05:25 skeletal medicine so it was chronic joint dysfunction and he did a specialized
0:05:29 type of medicine called prolotherapy and regenerative injection therapies the
0:05:31 modern version of that is stem cells you’ve probably heard of stem cell
0:05:35 injections I’m sure everyone has by this point platelet-rich plasma is another
0:05:40 one and that’s what he specialized in but it’s not just about shooting fancy
0:05:43 substances into people’s joints you have to get the person into a healing state
0:05:47 first so you need them optimized so that they want to heal so that means
0:05:51 hormones that means nutrition that means lifestyle those things are far more
0:05:56 critical to get lined up then it is to start shooting fancy substances into
0:05:59 their joints even if those substances come from their own body even if we’re
0:06:01 sucking out their own stem cells and we’re sucking out their own blood and
0:06:04 we’re using those it’s far more important that you get the person in an
0:06:10 optimized state so that they want to heal so I you know I’d ask patients if
0:06:15 you cut your fingertip off or just sliced yourself terribly do you heal well and
0:06:18 if they said yes they were a wonderful candidate for those types of injections
0:06:21 if they did not then they weren’t because they weren’t in a good healing state at
0:06:25 that point so my job was to get them in a healing state and then to apply the
0:06:30 treatments what is a healing state it’s when you fall down and you don’t fall
0:06:34 apart it’s when you get sick with something and you get over it it’s
0:06:37 when you cut yourself and you heal readily and you don’t you know succumb to
0:06:43 terrible infections and I think we’ve ended up as a society where the norm has
0:06:48 become to be somewhat immunocompromised I think a lot of people are walking
0:06:52 around not not you younger folks but at least in the US a lot of people are
0:06:56 walking around in this sort of semi-immunocompromised state much of it is
0:06:59 due to metabolic dysfunction which is something he was always drilling into me
0:07:07 what is metabolic dysfunction it is when your metabolic health at its core is
0:07:12 the ability to take in the foods that you eat and assimilate them properly so
0:07:15 if you were to eat proteins and fats and carbohydrates you would turn them into
0:07:18 the fuel that they need to be you would turn them into the proteins in your body
0:07:26 that they need to be when that goes awry which is almost a hundred percent of
0:07:31 US adults at this point from what the data is showing things don’t go so well
0:07:35 and so what that leads to this metabolic dysfunctional pattern leads to insulin
0:07:40 resistance which is essentially pre-diabetes which is the long game
0:07:46 into type 2 diabetes and we’ve completely normalized that process at least
0:07:50 during my lifetime I’ve watched that happen I’m 50 years old so I’ve watched
0:07:54 this happen especially since I got into medicine working for my mentor Dr. Rick
0:08:00 watching folks go down this pathway of normalization into type 2 diabetes and
0:08:04 it’s not until they get there that the doctor says oh you have type 2 diabetes
0:08:09 we got to do something about it here’s your pills and there’s 15 to 20 years of
0:08:12 legwork that can be done before that happens and that’s where I think
0:08:16 naturopathic medicine really shines and where preventative functional medicine
0:08:19 all of us are in the same camp we’re all doing the same thing we’re really trying
0:08:22 to just help the patient in front of us not so much the disease process we’re
0:08:26 trying to make sure that the person’s optimized so that they can become more
0:08:30 resilient so that their immune system works properly so that the foods that
0:08:34 they eat are assimilated properly and they don’t end up in a cellular milieu of
0:08:39 disaster is there like a fundamental belief that you have about human beings
0:08:46 how we heal how to be healthy and the body I guess that you think is in
0:08:50 contrast or conflict the current system like a set of fundamental underlying
0:08:55 beliefs because we all have like a set of sunglasses on our lens of how we see
0:08:58 the world yes and what I’ve obviously learned from doing this podcast is
0:09:03 everyone seems to be wearing slightly different lenses you know as to their
0:09:09 view on health this the healthcare system humans healing society what are
0:09:11 those sort of fundamental underlying beliefs that you have that’s a great
0:09:17 question I think that in traditional naturopathic medicine the purists would
0:09:20 tell you that there’s no room for pharmaceuticals and that you must only
0:09:25 go with nature the healing power of nature stoke the individual’s
0:09:28 vitality that’s very important in naturopathic medicine we’re looking at
0:09:32 the vitality of an individual some would call that an aura I think that’s a
0:09:37 little too esoteric it is when you look at someone are they are they glowing
0:09:41 vitality do they look healthy you can see it I know you can everyone can see
0:09:43 it when you actually pointed out to people do they look healthy or they
0:09:47 sort of walking around in grayscale right and I think a lot of people these
0:09:51 days are unfortunately walking around in grayscale because they’ve sort of you
0:09:55 know we’ve all been listening to the mainstream narrative and the food
0:09:58 supplies busted this has been going on for decades my mentor was talking about
0:10:01 this decades ago and nobody was listening and now people I think are
0:10:04 starting to get hip to it because we’ve got the internet we’ve got podcasts like
0:10:07 yours and mine and where we’re trying to get the you know the information out
0:10:13 and it’s the inherent ability of the body to heal however I do think there’s a
0:10:16 place for pharmaceuticals and I have a license to prescribe in the state of
0:10:20 Oregon and I’m not afraid to use it because in my mind and the way that my
0:10:24 mentor taught me is somebody comes in and they’re on this many pharmaceuticals
0:10:28 I mean I’m 50 the average person my age is on five different pharmaceuticals at
0:10:32 this point which is crazy to me and I don’t know what the stats are in the
0:10:35 UK but I can’t imagine they’re tremendously better so they come in on
0:10:39 all these drugs and their lifestyle is in somewhat of shambles and so my job is
0:10:43 to optimize lifestyle so that I can get these down to the lowest or to nil
0:10:48 ideally we could get them off but if they need a little something then great I
0:10:53 was also taught by him to implement longevity medicine which is hormones and
0:10:57 making sure that people are able to maintain physiologic levels of optimal
0:11:01 hormone function as we age which is really important to aging well and so
0:11:05 it’s just kind of a mix of using the best of nature and that science has to
0:11:09 offer and treating the person in front of you of all the case studies that you
0:11:15 have in your mind experience and in your past is there one that you are most
0:11:21 proud of it was 2019 my career was really taking off and my mom kept telling me
0:11:27 that she didn’t feel good and I was like my mom is a rock my mom’s my mom’s like
0:11:31 comes up to here on me I call her my little mama and she just chugs along and
0:11:34 I was like oh she’ll be fine she’s like no I really don’t feel good and I kept
0:11:37 blowing her off because I was too busy and I was on planes all the time and
0:11:40 traveling all the time and I was never home and my mom came to visit me at my
0:11:48 house and she came out of the bathroom and she said she’s like I like I can’t
0:11:54 hold my bowels like I can’t I’m so sick and so I immediately started testing her
0:11:58 and she had Crohn’s disease and my grandmother had died of Crohn’s disease
0:12:01 and several people in her side of the family had died of Crohn’s disease and
0:12:05 I just hadn’t put two and two together that my mom may have had but she had all
0:12:08 the symptoms like growing up she had all the symptoms and I just never put it
0:12:13 together and it was hitting her it it rears its ugly head when folks hit their
0:12:18 elder years like in their 70s they call it you know colitis of the elderly and
0:12:22 people basically get it and die they just shit themselves to death and so my
0:12:28 mom was in it and I was like oh no and I pulled out everything I had and I have
0:12:33 access to some incredible regenerative substances that you know most people
0:12:40 don’t and I can use them off-label in ways that you know in most people don’t
0:12:45 even think to do and I threw everything I had at her because I knew if I’d
0:12:49 center into the allopathic system they were gonna do a colonoscopy on her and
0:12:53 what that does is they flush you out before they do the colonoscopy and if I
0:12:56 if her flora were to get flushed out of her gut at that point I don’t think she
0:12:59 would have come out of the hospital because they end up getting secondary
0:13:03 infections and so I pulled her out of it I got her out of the really acute phase
0:13:07 and then I immediately referred her to my colleague who is a brilliant physician
0:13:10 naturopathic physician and I was like take over I’m not I don’t want to manage
0:13:16 my mom but I needed to get her I I knew that it was the skill set that I had in
0:13:22 particular that was gonna pull her out of that and so we did it and she came to
0:13:25 me one day after she was better and she was stabilized and she said you saved my
0:13:31 life and at the time I was really bitching about my half a million dollars
0:13:34 of student loan debt that was just compounding and compounding and
0:13:38 compounding and I was really frustrated by the fact that I couldn’t get on top
0:13:41 of it and I had at that point spent like a hundred thousand dollars paying off my
0:13:45 loans and they were still at the same level I mean it’s just criminal that
0:13:50 system and she said you saved my life it was worth every penny you know and then
0:13:53 my daughter turned around who had just gone through a very difficult time
0:13:59 herself and she said you saved my life to mom this year and I was like well if
0:14:02 that was what it cost to gain the knowledge that I gained to save my
0:14:06 daughter and my mother and then my dad was like you save my you bailed me out
0:14:11 many times and I was like okay that’s so it was kind of it was just kind of
0:14:15 ironic that was the end of my big clinical career you know when I had my
0:14:19 big brick-and-mortar with a high volume patient base and all of I still see
0:14:24 patients but not at that level and so that was really I was like thank God I
0:14:29 had the knowledge and the tools and the know-how to and the fearlessness to
0:14:32 apply some of the therapies that I applied the way I did to in terms of
0:14:37 before and after what sort of picture of health would I observe if I saw her on
0:14:42 that day when she walked out of the toilet versus you know after the the
0:14:46 variety of different therapies that you applied well this is a good story
0:14:50 because she was super gray and super thin and my mom has always been kind of you
0:14:54 know hippy and curvy and I mean she’s we’re built different and she’s she’s
0:15:00 the more you know she’s the curvy one and she was just rail thin and gray and
0:15:03 all of her hair was falling out I mean she just I can’t believe I missed it I
0:15:06 can’t believe it went on that long that I didn’t see it and I I still carried
0:15:11 guilt to this day and I always apologize to her for being too busy to I can’t
0:15:16 believe I let my stress level get so high that I didn’t see it you know and then
0:15:20 she ended up on a slew of pharmaceuticals that were too expensive to get in
0:15:23 the United States so she had to get them from Canada so her naturopathic
0:15:26 physician is managing her so she’s getting medication a very expensive
0:15:31 medication from Canada and she’s doing okay and then in the last nine months I
0:15:38 put her on the tiniest droplet of semaclutide which is a zempec and she
0:15:43 is phenomenal all of her joint pain is gone her guts completely regulated and
0:15:47 normalized she is down on a minimal dose of this medication that she’s getting
0:15:51 from Canada she’s still taking it but it’s a tiny dose her cognition has
0:15:54 improved significantly because through this process she was starting to get
0:15:56 low-grade dementia whether she realizes that or not my daughter and I were
0:16:02 noticing it we were like is grandma okay and so when people come at me for
0:16:07 talking about micro dosing ozempic I will not back down because my mom is
0:16:11 solid and it’s the tiniest amount and she even said to me just the other day
0:16:14 before I was coming on the show I was telling her I was stressed I was trying
0:16:18 to get ready for the trip you know overseas and she said you know I was so
0:16:22 stressed out before you put me on semaclutide because my dad’s health is
0:16:26 very poor and she said I was so stressed that I really felt like it was gonna do
0:16:30 me in like I was at capacity and you put me on the semaclutide and all of the
0:16:37 anxiety and stress just dropped away and I was like that’s cuz it’s calming to
0:16:42 neuro-inflammation which is secondary to chronic gastrointestinal diseases when
0:16:46 the gut is inflamed the brain’s inflamed so she was dealing with all this
0:16:50 chronic brain inflammation all this gut inflammation and she’s on this tiny
0:16:56 little dose of ozempic and she’s very solid and she’s her colors back she’s
0:17:01 filled in again she’s curvy again she’s eating normally she does I mean she
0:17:05 couldn’t eat hardly anything ever for years and so now she’s back to eating
0:17:08 very normally she’s still got to watch what she eats but you know it’s not a
0:17:14 free-for-all but she is she’s back the other I guess glaringly obvious case
0:17:17 study for your work but also I think many of the things we’re going to talk
0:17:22 about like micro dosing is MPEC is you yeah because as I read through your
0:17:25 story from your childhood years through your teenage years and even in
0:17:29 university and then even later into your career and I guess also now because you
0:17:34 mentioned that you still deal with chronic pain you are your own case study
0:17:39 I am can you give me a view of of the struggles you’ve been through in terms
0:17:43 of your health and really where that started what was the sort of first
0:17:48 first instance where you experienced the pain the trauma etc etc so I always had
0:17:55 stomach aches always since I was a child always and was hit with really pretty
0:17:59 severe anxiety I didn’t know what it was at the time but it was anxiety and I
0:18:05 started getting chronic pain in my teenage years and I out of nowhere when
0:18:10 I was about 15 the lights went out on me I just became extremely suicidal and
0:18:14 depressed out of nowhere I mean it was like somebody just switched up lever I
0:18:18 had moved to Oregon from Southern California I do believe that the lack of
0:18:23 light was massive I think that people really I’m really starting to appreciate
0:18:27 it’s taken me all these decades but light deficiency is a huge issue that
0:18:30 we’re not no one’s talking about a few people are but you’re talking about
0:18:34 like vitamin D production as well right there oh that was huge so that took
0:18:38 years you know nobody was talking about that it was not until decades later I
0:18:42 was sitting in Nature Pathic Medicine School I was in college and I think I
0:18:47 was in year three of that program and this doctor Dr. Alex Vasquez came to
0:18:50 lecture at ground rounds and he started talking about vitamin D and sunlight
0:18:55 deficiency and I had been kind of low-grade looking into sunlight
0:19:00 deficiency because it turns out the hospitals of your really would optimize
0:19:03 sunlight and they would have sun porches I don’t know if you’ve seen the photos
0:19:06 they would roll all the kids out and all of the convalescing ill people out I
0:19:11 mean that’s how people survived in 1918 flu was the ones who got sunlight and
0:19:14 the ones who were able to go to these hospitals and they would build the
0:19:17 hospitals to optimize light exposure inside the ward because they knew it
0:19:20 kept the bacteria counts down and I mean even if they didn’t know what bacteria
0:19:24 was or what was happening they knew that when sunlight penetrated people were
0:19:28 you know healthier and things were cleaner and infections didn’t seem to
0:19:34 spread and so I hit my 20s and long story short I was rocking psoriatic
0:19:37 arthritis for decades before I ever figured it out and it really culminated
0:19:41 for me I went through a lot of chronic pain I went through a lot of misery I
0:19:45 went through a lot of autoimmune issues and then I got everything dialed in I
0:19:50 thought I had it handled interestingly autoimmune disease will flare and will
0:19:55 recede and flare and recede and it’s kind of on cue like you’ll see it around
0:19:58 10 to 11 years old especially with things like Crohn’s disease you’ll see
0:20:02 these little glimmers pop up for kids and then it goes away and then you’ll see
0:20:05 them present in their teenage years and often they’ll present with you know
0:20:08 mental emotional issues and not so much the gastrointestinal issues but it’s
0:20:12 the same process going on in the body and then it’ll go away and then it might
0:20:16 flare again postpartum because of that big hormone surge that happens with
0:20:20 childbirth and then it’ll go away and then it’ll come back with a vengeance in
0:20:24 menopause as the hormones again shift majorly and that’s what was
0:20:27 happening for me and then all of the stress of pushing back against the
0:20:33 narrative really caught up with me and I was nothing that I knew to do was
0:20:36 working so the whole protocol I put my mother through was not working for me
0:20:41 nothing was touching it and that is how I came to start studying GLP1 agonists I
0:20:45 started I was researching anything that would calm neural inflammation because
0:20:51 at the end of the day diseases down here are coming from here and when the
0:20:55 brain’s on fire and the brain’s inflamed the immune system gets sent
0:21:02 completely sideways and the downstream processes culminate in autoimmune
0:21:08 disease pain hormonal disruption you name it and so I that’s how I ended up I
0:21:13 literally put into Google GLP1 and neuro inflammation and all these studies
0:21:19 showed up and that’s what got me going two questions there so GLP1 is a zempec so
0:21:24 it’s yes it’s the peptide that the body makes naturally we make it in the brain
0:21:28 and we make it in the gut but if somebody’s had a life of chronic gut
0:21:33 inflammation I don’t think they’re making it so well in the gut and a zempec is
0:21:39 just a it’s several versions down in the generational line of these peptides
0:21:45 called incretins they’re they’re a whole family that started way back 20 some
0:21:50 years ago and they’ve just gotten a little bit nicer with less side effects
0:21:56 and longer half-life as we go along the journey so the last decent one was
0:22:00 loraclutide although compliance was low because it made people feel really
0:22:03 terrible and they had to inject it too frequently I think it was daily or I
0:22:06 think that’s how it is still and then somaclutide is a newer generation
0:22:10 terzepotide is a newer generation and so they’re they’re just getting a little
0:22:15 more potent and I don’t mean potent in a pharmaceutical way I mean they’re
0:22:19 starting to realize how these work and they’re they’re getting craftier with
0:22:22 not only keeping them in the body for the time that they need so the half-life
0:22:27 gets longer but they’re finding in the suite of signaling peptide hormones
0:22:31 that are involved with appetite and with metabolic health and insulin
0:22:36 secretion and insulin sensitivity they’re finding better and better ways to
0:22:41 combine these to get optimal function with the least amount of side effects
0:22:47 okay and at that moment in your life where you started googling GLP1 and
0:22:56 inflammation etc if I was a fly on the wall in your life at that moment what
0:23:02 would I’ve what would I’ve seen what was the sort of picture of desperation or
0:23:07 you know so 2021 I spent most of that year on my back because I was in so much
0:23:12 pain it was crazy and my husband when he met me he met me in 2019 and we got
0:23:17 married in 2020 and I told him I had chronic pain and I told him I had a
0:23:20 funny immune system but he had never seen it like he’d never seen it full
0:23:24 force and he got to see it that year he was like wow so this is what chronic
0:23:27 pain looks like I mean it was devastating and my spine was fusing and
0:23:31 I’m active like I do Pilates and I dance a lot and I hula hoop and I roller
0:23:35 skate and I lift weights and I’m you know moving and shaking I was not moving
0:23:39 and shaking in 2020 I was 2021 I was flat on my back on the couch and I
0:23:47 remember by the end of 2021 thinking if this doesn’t get better I think I’m
0:23:53 gonna kill myself like I couldn’t do it anymore like I just couldn’t live with
0:23:57 that level of pain and my spine was fusing and I could feel it and I kept
0:24:01 trying to tell everyone something is wrong and my chiropractor friends were
0:24:04 great but they knew musculoskeletal medicine and my naturopathic friends
0:24:08 were great but they knew systemic medicine and I needed me I needed my
0:24:11 brain on the case like someone who had both right and I just couldn’t get on
0:24:17 top of it and then finally I I don’t know how or why I I went kind of into the
0:24:20 story oh I know what it was I broke out with psoriasis I broke out with psoriasis
0:24:24 all over my scalp and I was like oh this is what this is this is psoriatic
0:24:28 arthritis which turns out to be one of the most painful musculoskeletal auto
0:24:32 immune conditions you can have it it’s worse than rheumatoid arthritis on the
0:24:36 pain scale from what the study shows so I was like okay now that I know what I’m
0:24:39 dealing with what can I do so I started pulling out all the stops and all the
0:24:44 things I knew to do low dose naltrexone exosomes you name it I was doing
0:24:48 everything it really wasn’t bringing it down or it would work for a minute and
0:24:53 it would it would it would wear off and so I was getting desperate and my pot I
0:24:57 have a podcast and my podcast producer said you got to do an episode on
0:25:01 Ozympic and I was like I don’t I don’t like talking about weight loss I really
0:25:04 don’t like talking about weight loss it people get so emotionally triggered and
0:25:10 it’s a big topic and it’s nuanced and it’s not as simple as people want to make
0:25:13 it be and in my functional medicine world people want to make it so
0:25:18 simplistic just exercise more and eat less and take these supplements and it’ll
0:25:22 go carnivore and it’ll all go away it’s not that simple there’s genetic
0:25:27 components there’s brain components there’s epigenetic components and it was
0:25:31 like the Pandora’s box I didn’t want to open and so finally I was like okay fine
0:25:34 I’m gonna start researching these and I was sitting I was laying on the couch
0:25:39 on my back and it’s 2023 at this point but I’m still having to take frequent
0:25:43 breaks right on my back so I’d go exercise and I’d have to lay down for
0:25:48 three hours so I’m googling and I look up GLP1 and neuro inflammation because I
0:25:53 always start there I always start with pain neuro inflammation and immune
0:25:56 activation I always want to know what any substance does in those because that’s
0:26:00 my world right because that’s what I did in clinical practice and I googled that
0:26:06 my husband’s in the kitchen and I was like holy shit and I turned the phone
0:26:08 around and I was like look at this and he’s like I don’t know what that means
0:26:13 babe and I was like this is not what they’re telling us like this is not what
0:26:17 because that was at the height of mainstream media and all the clickbait
0:26:21 headlines and you know mom is overdosing on ozempic and people’s
0:26:26 stomachs are paralyzed forever and I was like so then I started of course looking
0:26:30 at all that like is that for real like are they really getting gastroparesis
0:26:35 forever no so I start going into all the data and I just that was it it was like
0:26:40 the rabbit hole and it that was May of 2023 and I’ve been knee-deep in it ever
0:26:45 since just consumed by any and all information and then of course everybody
0:26:49 start I started doing podcast about it on my show and everyone’s sending me all
0:26:52 the information and hundreds of people are reaching out to me telling me these
0:26:56 really profound stories and changes in their health that have nothing to do with
0:27:01 weight loss or diabetes and so that was it I was like I got I got bit by some
0:27:07 kind of well you know I don’t like propaganda I don’t like when I hear
0:27:11 everybody saying the same thing it makes me suspicious you know when
0:27:17 everyone’s running in one direction screaming this is evil this is this is
0:27:21 this is you know the worst thing ever I was like I don’t know this has been
0:27:25 around for 20 some years not some acclutide but this version of medication
0:27:30 this family of medication and so I don’t know it’s like I’m not buying this I’m
0:27:34 gonna find out what the truth is and so I called every doctor I knew that might
0:27:39 use it I called every pharmacist I knew that might use it nobody was seeing any
0:27:43 of these horrific side effects like the stories you were seeing on the media
0:27:47 currently what was that summer that was really it came to like full-height
0:27:52 summer of 2023 I think that was when everybody was losing their minds about
0:27:56 it the minute they started talking about weight loss people started losing their
0:27:59 minds about it which I find very interesting and what I was finding in
0:28:04 the literature was not at all adding up to what I was hearing and then there were
0:28:09 all of these other benefits that were just mind-blowing you know benefits
0:28:17 on healing and reversing type one diabetes healing and reversing neuro
0:28:22 cognitive conditions like Parkinson’s and Alzheimer’s efficacy with alcohol
0:28:26 cessation people who were you know alcohol abuse syndrome using it for
0:28:33 that people who also had the this type of it HLA B27 it’s a genetic propensity
0:28:39 towards these spondyloarthritis is like psoriatic arthritis rheumatoid arthritis
0:28:44 those kinds of things having showing efficacy for that and as I started
0:28:49 speaking out about it I was getting messages back from people telling me
0:28:52 their stories hundreds and hundreds of people telling me their stories and I
0:28:55 and then seeing what was happening with my patients so I started applying it to
0:29:00 everyone I was treating for different reasons at different doses very tiny
0:29:04 doses though very little bits and just seemed really profound changes in people
0:29:10 and I it’s not what we’re hearing and I don’t think that the way also that it’s
0:29:16 being done in the standard model is ideal for everyone I think a lot of
0:29:19 people are being dosed too high too fast and I think a lot of people are being
0:29:22 overdosed because at the end of the day it’s a hormone it’s a peptide signaling
0:29:27 hormone and so people are being cranked up on doses very quickly there’s a 16
0:29:32 week escalation and they go from this amount to this amount very quickly and
0:29:36 in the journey many people are reporting horrific gastrointestinal side
0:29:41 effects which are real but it’s not the peptides fault it’s the it’s a peptide
0:29:45 at the end of the day as well which is I can explain what that is yeah if you had
0:29:49 to explain what a Zempec is or we’ll go over your you know this this compound is
0:29:55 just to a 10 year old yeah okay how would you explain it so you eat amino
0:29:59 acids you eat protein and it breaks down into amino acids yeah and amino acids
0:30:04 link up with peptide bonds into chains called peptides and then peptides peptide
0:30:09 bond it’s just a simplistic bond that binds to amino acids together so it can
0:30:13 be broken pretty readily with different enzymes and that’s in my body the
0:30:17 peptide bond is in my body yeah so your body has all these enzymes present and
0:30:22 the amino acids link up very simplistically into different chains
0:30:27 and then those chains of amino acids are called peptides and peptides link up to
0:30:31 form proteins and your body is made of proteins your whole body all of your
0:30:35 tissue is made out of proteins and your cellular receptors are made out of
0:30:38 proteins everything’s made out of proteins so if you go backwards those
0:30:43 smaller versions are the amino acids I’m sorry are peptides and the smaller
0:30:48 versions of that yet are the amino acids so we eat protein we break it down into
0:30:55 amino acids and we reconstruct it into more protein and so peptides are these
0:30:59 chains of amino acids that we’ve got all different types of therapeutic peptides
0:31:02 and they insert themselves where they need to go to do what they need to do
0:31:07 so that’s it at the end of the day and what so what’s the Zempec in that is
0:31:12 Zempec is a peptide it’s a peptide and it’s made in our L cells of our gut which
0:31:18 line from the most proximal to the distinal small intestine and it secrete
0:31:23 these cells secrete GLP1 in the presence of glucose which is sugar when we eat
0:31:28 sugary foods or food well all carbohydrates break down into glucose so
0:31:33 whenever we eat glucose and they respond actually when a bolus of food so the
0:31:38 mechanism of a blob of food going through our guts actually gets these cells to
0:31:43 trigger however I have tested thousands of people’s guts in my clinical
0:31:47 practice in my clinical lifetime and people’s guts are a mess most people
0:31:51 have compromised digestion so I don’t think their L cells are working optimally
0:31:57 in many cases and we also have literature good solid science to show that
0:32:01 those who are suffering with obesity type 2 diabetes and fatty liver and that
0:32:07 whole metabolic syndrome you know groupage those folks are GLP1 deficient
0:32:14 so when I take a Zempec it’s causing my gut basically my body to release GLP1
0:32:19 no it is the GLP1 oh it is the GLP1 yep so we’re not causing the gut to do
0:32:24 anything we are mimicking the actual peptide okay so it’s got the same sort
0:32:30 of atomic structure my body thinks it’s GLP1 I guess it is as far as
0:32:34 things are concerned and then the GLP1 is doing what to me well so it’s
0:32:39 somaculotide for instance is bio-identical to the GLP1 that our
0:32:43 body secretes it’s the same except it’s been tweaked with a little bit they’ve
0:32:48 added some lipids to it to make the half-life longer that last longer so
0:32:51 normally GLP1 would be secreted from our cells it’s also secreted from our
0:32:55 brain which we got to get into because that’s where I got really excited it’s
0:33:00 secreted from our body and it’s broken down very quickly and so these newer
0:33:07 versions of these incretin hormones or incretin peptides are broken down at a
0:33:14 slower pace okay and then what does GLP1 do it does all kinds of cool things so
0:33:21 it most notably and what it’s known for is to decrease appetite and that happens
0:33:26 centrally in the brain yeah it slows gastric motility so it slows things down
0:33:30 so you feel fuller for longer that’s at higher doses that doesn’t always need to
0:33:37 happen and that is what it is known for and it also has induction of it plays
0:33:41 with the cells of your pancreas and it gets them to secrete insulin at the
0:33:46 right time and so most folks are walking around and in some degree of
0:33:50 insulin resistance as they age and that is the beginning glimmers of type 2
0:33:56 diabetes and so GLP1’s help that process it helps sensitize the cells to the
0:34:01 insulin and it helps secrete the insulin when needed and when you were
0:34:08 struggling in 2023 yeah you started taking a Zempec
0:34:16 semaglotide one of these brands yeah what impact did I have on you so I got a
0:34:20 compounded version because I thought that the starting dose let’s back up the
0:34:24 brand name the prescription that most people are familiar with are these
0:34:28 little pre-filled pens yeah and the pens only come in certain doses you can’t
0:34:32 control the doses you start at the lowest dose that they offer and then you
0:34:35 have to escalate from there or if your doctor’s cool they won’t make you
0:34:38 escalate too much but either way you don’t get to go lower than the dose
0:34:42 that it starts and it starts at 0.25 milligrams I thought that that was way
0:34:46 too high especially for someone like myself I’m very metabolically optimized
0:34:50 I have good muscle mass I have very good bone density I have my labs look
0:34:54 beautiful I’m hormonally optimized I’m on bioidentical hormone replacement I’m
0:35:00 very active I exercise often my sleep is good and I thought my thinking was I
0:35:06 wonder if some of us are actually a little GLP one deficient from whether a
0:35:13 life of not because we have obesity diabetes and fatty liver there’s
0:35:16 different reasons why those folks would be deficient insulin at high levels
0:35:20 itself will actually induce some GLP one deficiency it’ll it’ll decrease in GLP
0:35:26 one signaling my thinking was I wonder if folks are just genetically or maybe we
0:35:29 got ourselves there through chronic illness whatever it may be I wonder if
0:35:33 there’s a little bit of a deficiency what if I supplement this peptide like I
0:35:37 would a hormone which the way I do that is I give people the lowest dose
0:35:42 necessary to achieve a physiologic impact that’s favorable and then I cap it
0:35:47 so if you need a little bit of thyroid the standard model would have you take
0:35:51 well you know the algorithm says you have hypothyroidism so we’re gonna give you
0:35:55 this much and we’re gonna be this exact drug in my world we compound what we need
0:35:59 maybe you need a little more t3 than t4 maybe you need a tiny dose maybe we
0:36:02 titrate you up until you start getting a little symptomatic and we’re like yeah
0:36:06 let’s back it down a little so my thinking was to use it that way so I
0:36:09 asked everyone I knew are you using this for anything other than appetite
0:36:13 suppression or weight loss or diabetes and they all said no nobody really was
0:36:16 none of my colleagues were anyway and they were all starting at a dose that I
0:36:21 still thought was too high so I started myself at a tiny little dose and my
0:36:27 first impact was brain clarity within days my brain cleared I can’t even
0:36:32 explain it brain fog was definitely starting to happen I think it was the
0:36:35 psoriatic arthritis and I think it was the I think it was post COVID you know I
0:36:39 think our brains all got hit pretty hard by that and I think it was chronic
0:36:44 stress and I think it was menopause and I was sort of in this I’m a high
0:36:47 functioning kind of boss babe and I couldn’t get my work done and my team
0:36:50 was going crazy because I couldn’t remember what I told them and you know
0:36:52 they’re calling me and they’re like we already did this we already had this
0:36:56 conversation what is wrong with you so I was like damn it this isn’t gonna work
0:37:00 for me I can’t be rolling the way I’m rolling and trying to run all my
0:37:04 businesses and have brain fog like this so that was the first thing I noticed was
0:37:07 clarity of thought brain fog went away anxiety immediately dropped which I
0:37:11 didn’t even realize I had it’s just a calmness took over me which was so
0:37:18 amazing and within two weeks my pain was down significantly significantly and
0:37:21 what I noticed was everything was starting to move in pop again so I was
0:37:27 getting mobility back and by week two I wanted to move again so this version of
0:37:30 me that just wanted to like go do my workout go to my work and then lay down
0:37:35 on my back I wasn’t that doing that anymore and I immediately like signed
0:37:38 back up for Pilates and I found myself dancing and who looping around the house
0:37:44 again and I found myself just being much more active and slowly but surely the
0:37:48 destruction sort of fell away because I had been in a pretty destructive immune
0:37:52 process for a couple years there and it just has it’s taken me I think it’s been
0:37:56 almost a year now and it’s just slowly but surely dropped away I also noticed a
0:38:00 little bit of weight loss which I had gained some weight over the past couple
0:38:05 years I think it was chronic stress was doing a number on my metabolism and you
0:38:09 know you hit that 50 year old mark and things get tough so I had some weight
0:38:13 loss fall away I got right back down to my fight and weight I’m like literally the
0:38:18 size I was in 2019 going into all of this and so I quickly started putting
0:38:25 people on it and very similar responses all of them had a little bit of fluff
0:38:28 but nobody was on it for weight loss everyone had a little bit of weight fell
0:38:32 right off got back down to a good weight my mom I was particularly concerned
0:38:35 about because I didn’t want her to waste away again I didn’t want her vomiting I
0:38:37 didn’t want her having any gastrointestinal symptoms I wanted all of
0:38:42 those to resolve it shifts your gut microbiome to a more favorable microbiome
0:38:46 if you do it right and so and we have the data on that so I was very slow and
0:38:49 cautious with her I don’t want her losing any muscle mass and everybody just
0:38:56 had these profound impacts my daughter’s skin cystic acne I mean a decade of
0:39:01 severe cystic acne the point where she did not enjoy her teenage years and she
0:39:06 was suicidal from it I mean just hiding behind her hair for years her skin I
0:39:10 remember seeing her after three weeks on it and I was like your skin is porcelain
0:39:16 what happened all of her PCOS symptoms reversed my husband didn’t want to drink
0:39:20 anymore the guy is a known alcoholic he was like not interested in alcohol his
0:39:24 blood pressure regulated out I mean just all of these little things started
0:39:30 happening and I started seeing similar effects in my patients and then I at
0:39:33 the same time I was posting about it and talking about it on my podcast and
0:39:36 people were messaging me telling me these profound stories they were like I
0:39:40 went on it for weight loss or I went on it for metabolic dysfunction or type 2
0:39:43 diabetes but here’s all the other things that started happening and then
0:39:46 people started telling me they were getting pregnant on it and you know when
0:39:50 they had been infertile and gone through rounds of IVF that were not working and
0:39:54 just all of these amazing stories and so of course I keep I have to research that
0:39:59 and do more information on that and it’s just been I’ve just been unwinding I
0:40:05 feel like I’m unwinding a story that isn’t being told so what is that story
0:40:09 to summarize what is that story that’s not being told that you’ve come to
0:40:15 believe these peptides are healing they are anti-inflammatory and they are
0:40:18 regenerative and they have a profound impact on our immune system in a
0:40:25 positive way and they don’t just cover up and mask the insulin resistance in the
0:40:29 metabolic dysfunction that leads to type 2 diabetes they actually heal it how
0:40:34 do you know that well interestingly as this year has gone on more and more
0:40:39 studies have come out and we’re starting to see it so many of the hypotheses I
0:40:42 had about it are starting to show themselves in good clinical data and
0:40:47 good studies and I’ve seen it with my patients and I’ve seen it with myself so
0:40:53 I am now able to go off of it at first I could only go off of it for a short
0:40:56 amount of time and my psoriasis would come back that was the first symptoms I
0:40:59 would start getting skin issues and I usually get it around my scalp line
0:41:05 little itchies that would come back within seven to ten days I am now able
0:41:10 to go a month without it and absolutely no symptoms and the second I start to get
0:41:14 brain fog or a little bit of pain I go back on I cycle it like I would any
0:41:17 other hormone I don’t know if you’ve had any guests on talking about hormones but
0:41:23 they’re done best when you cycle them because receptors get saturated and
0:41:26 when you saturate a receptor with a hormone or after a while the cell will
0:41:30 stop listening and so you don’t want to just keep flooding a cell or a body with
0:41:35 a hormone you want to take it away and let those receptors pop back up and so I
0:41:38 think done correctly and done in an elegant way that’s just reasonable
0:41:44 clinically reasonable I think that we can actually start to heal some of these
0:41:50 chronic lifestyle diseases that are so rampant and it makes me wonder if we
0:41:54 would need less and less and less of the common pharmaceuticals that are being
0:41:57 handed out like candy the lifelong pharmaceuticals people go on statin
0:42:01 drugs or they go on blood pressure medications and no one says boo they’re
0:42:03 on it for life oh here’s your metformin for your type 2 diabetes you’re on it
0:42:09 for life I think done correctly and also the neuro regenerative process that
0:42:13 these induce in the brain they actually regenerate neurons
0:42:19 neuroplasticity is this concept where when the brain when you do something
0:42:24 enough your brain will hardwire into that and so any habit good or bad that
0:42:28 you consistently do or any thought process you consistently have if you’re
0:42:31 chronically depressed you’re chronically negative or you know I mean you
0:42:35 know this you’re you’re self-optimizing yourself all the time and growing and
0:42:39 trying to grow and be better you’re plasticizing your brain and
0:42:42 hardwiring that circuitry so it’s getting easier for you and you continue to
0:42:48 seek knowledge these peptides offer people a window of opportunity of not
0:42:50 only giving them the onus of control back because there are some mechanisms in
0:42:54 the brain and the dopinergic pathways that are giving people the they’re back
0:42:58 in the driver’s seat they’re back in control of what they’re doing but it’s
0:43:02 also inducing this neuroplasticity so if they are to implement really positive
0:43:07 lifestyle habits during the period of time that they’re on it they will
0:43:10 hardwire that into their brain so it’s like opening a window of opportunity for
0:43:14 somebody to completely change their life you mentioned some studies there that
0:43:19 have really supported your thesis that as MPEC is more than just a weight loss
0:43:22 drug and that has these other sort of regenerative properties and these
0:43:25 healing properties what are some of the studies you’ve got some something in
0:43:28 front of you there that you brought with you what are some of these studies that
0:43:33 highlight this in your view well so there’s one study in particular that I
0:43:37 don’t have the title ever written down where they looked at all of the data on
0:43:40 all of the GLP1 agonists that are out there the different versions that I
0:43:44 mentioned and they went back through all of the studies and they looked at it
0:43:48 system by system by system and I gave your team a link to that and what they
0:43:53 found is I mean going from tip to toe neuro regeneration and anti-inflammation
0:43:58 in the brain they showed improvements in cardiovascular tissue we just had a
0:44:02 study come out at the end of 2023 called the select trial was a big one yes it
0:44:06 was sponsored by Novo Nordisk who’s the manufacturer of somactetide of I should
0:44:10 say of a Zempik and so people say oh don’t believe those studies it was a
0:44:16 well-done study it looked at individuals in their 40s who were overweight but did
0:44:20 not have type 2 diabetes and it showed a 20% reduction in severe
0:44:26 cardiovascular events so stroke and heart attack and and others and so then
0:44:29 people argued once that came out and said oh well that foof you know Novo
0:44:33 Nordisk did it and that would happen if people lost weight anyway right you’d
0:44:37 have improvements in cardiovascular disease well they just looked at the
0:44:41 data again and realized that those benefits were independent of weight loss
0:44:45 whether people lost weight or not they still had significant improvement in
0:44:49 cardiovascular outcomes which there’s just nothing we don’t have anything out
0:44:54 there that does that I found data showing regeneration of pancreatic tissue
0:45:01 beta cells in type 1 diabetics if given early enough so if a person is type 1
0:45:04 diabetes is an autoimmune condition where the pancreas becomes destroyed by the
0:45:09 immune system it’s different than type 2 we don’t have anything to help those
0:45:13 people it used to be called juvenile diabetes and then type 2 was adult
0:45:17 onset but now kids many many children are dealing with type 2 so it’s a big
0:45:20 mishmash but they’re very two different processes they shouldn’t even have the
0:45:27 same name anyway done early reversal of that pancreatic damage to the point where
0:45:32 people didn’t need to go on insulin and were able to have pancreatic healing we
0:45:38 don’t have anything that does that accept stem cells they at the end of 2023 they
0:45:44 had to stop the flow trial because this was a chronic kidney disease trial they
0:45:48 had to stop it because the control group they needed to be able to ethically give
0:45:52 the control group the substance because it was so effective it was so effective
0:45:56 at reversing chronic kidney disease and kidney failure that they needed to be
0:46:00 able to offer it to the control group ethically and not let them continue on
0:46:05 their journey of kidney damage so we’ve got this mishmash of studies and then
0:46:08 they’ve done little studies here and they’re looking at muscle for instance
0:46:12 it’s regenerative to muscle it’s regenerative to bone it’s regenerative to
0:46:17 our joints some of this is in mice some of it’s in humans it’s regenerative to
0:46:23 the testes and to sperm production and motility when you say regenerative to
0:46:28 say muscle when people talk about as impact one of the big concerns is that
0:46:33 you lose a lot of muscle right it’s not true I mean it is true I should let me
0:46:40 let me let me rephrase that any dietary intervention or bariatric surgery that
0:46:47 induces a severe caloric restriction will lead to about 20 to 35 percent muscle
0:46:51 mass or I should say lean mass loss so this is a little bit of a nuanced
0:46:56 conversation if you basically put somebody into a self-starvation mode they
0:47:02 will lose 20 to 35 percent of their lean mass lean mass is all the soft tissue in
0:47:06 your body so that could be your tendons and your ligaments and your brain and
0:47:09 they they clump it all into one and they’re looking at that and saying it’s
0:47:15 all muscle muscle is a percentage of that muscle isn’t all of your lean mass
0:47:19 right and so that kind of makes the thing the studies look bad there I
0:47:24 think the other thing that they don’t consider in that is pathologic muscle due
0:47:29 to metabolic dysfunction will be marbled with fat which does that mean
0:47:35 sorry well it’s like a faux-graw when you induce metabolic dysfunction in an
0:47:38 animal which is what they do in feedlots for cows often and they do it to geese
0:47:42 to get their liver fatty you will end up with this fatty infiltrate in the muscle
0:47:48 so the muscle goes from being this lovely striated linear beautiful pattern
0:47:54 to marbled with fat and that fatty infiltrate becomes very pathologic to
0:47:58 the muscle and it puts the muscle itself into an insulin-resistant state so
0:48:03 once the marbling occurs in the muscle it’s sort of a chicken and egg down hill
0:48:08 situation for the muscle and I do believe very strongly and I’ve been
0:48:11 preaching this for decades that once that process starts and it most often
0:48:15 starts in the thighs you’ve probably seen the pictures of the cross-section of
0:48:19 like this is an 80-year-old triathlete and his muscle looks really beautiful and
0:48:23 linear and then here’s you know the average 80-year-old and it’s really
0:48:27 marbled and the bone loss is significant and the fatty layer on the
0:48:32 outside is thicker but what’s most important in that photo is the marbling
0:48:35 of the muscle we don’t want marbled muscle that’s the beginning of the end
0:48:39 you also end up with fatty liver and you end up with fatty pancreas when you’re
0:48:43 in this metabolic dysfunction state this downhill journey that culminates in type
0:48:49 two diabetes and so one of the first things that happens when metabolic
0:48:52 health improves whether this is through dietary interventions lifestyle
0:48:57 strength training you name it is that fatty infiltrate starts to dissolve these
0:49:03 GLP-1 agonists induce that process of the fat dissolving and so I think that’s
0:49:07 part of the lean mass loss that they’re measuring they’re just measuring it as
0:49:12 lean mass loss but we’re also decreasing muscle size because we’re having the
0:49:17 fatty infiltrate start to burn itself up. GLP-1s have also been shown to
0:49:22 perfuse the muscle with angiogenesis so we get a vascular supply so that more
0:49:27 amino acids are available to the muscle so when they looked at aging muscle in a
0:49:31 human and they gave them GLP-1 agonist their muscle became healthier and less
0:49:34 pathologic because it started to actually get better blood supply and be
0:49:38 infused with the amino acids they were eating in the form of protein so it’s
0:49:43 and then there’s pathways that are impacted as well that are inducing
0:49:48 muscle protein synthesis so GLP-1s actually induce muscle protein synthesis
0:49:51 they don’t cause muscle wasting it’s the caloric restriction that’s causing the
0:49:56 wasting and they’re measuring it somewhat aberrantly does it make sense
0:50:00 that’s that’s the story I’m trying to weave here yeah so but how how can I
0:50:04 avoid the caloric restriction if I’m taking the GLP-1 agonist like some
0:50:07 like some aglitide or his MPEC you don’t dose it too high so you don’t crush the
0:50:11 appetite so the whole goal is to keep people at a dose where they still have
0:50:14 an appetite you don’t have to crush their appetite with it the way it’s being
0:50:17 dosed traditionally is they’re ramping it up really fast and they’re just
0:50:22 devastating people’s appetite with it and so people go from hungry and starving
0:50:27 to I don’t want to eat anything and so they don’t and then they often will eat
0:50:32 less healthy version I’m sorry they’ll eat less volume of a poor app of a poor
0:50:36 diet so they will continue to eat junk food only less of it they will continue
0:50:41 to eat the crappy foods they’re used to eating only less of it and I’ve heard
0:50:44 Johan Hari on your show talk about this and he’s a beautiful book that he wrote
0:50:48 his magic pill book he talks about that he found himself about five or six months
0:50:52 in and he was still just eating the same crap he was just eating less of it and
0:50:56 what needs to happen when anybody’s on this at any dose is they need to be
0:50:59 protecting their muscle with all their might they need to be strength training
0:51:03 and they need to be prioritizing their protein macros like those are the two
0:51:06 non-negotiables I don’t think doctors are always talking about that and I don’t
0:51:10 think patients are compliant with that if I start micro dosing there what you
0:51:14 know when I see less of the reward I see less of the cost but I wouldn’t will I
0:51:17 not also get less of the reward that the positive upsides that you’ve described
0:51:21 not if you’re doing all the other lifestyle things so like I said it
0:51:24 opens this window of opportunity where people feel much more in control because
0:51:27 there’s impacts on the brain that allow people to be much more in control of
0:51:31 their choices and of their thought processes and of their even of their
0:51:34 obsessions it’s very interesting how it works and so people are able to make
0:51:39 better choices and I think given that window of opportunity and introducing
0:51:43 these lifestyle interventions they’re gonna be much more open to it so we get
0:51:46 them exercising we get them eating better we get them doing all the things as you
0:51:51 know we get them optimizing their sleep we get them going on walks and meditating
0:51:55 and mitigating their stress all of those things are going to improve their
0:51:59 metabolic health so it’s a two-pronged approach and we don’t have to crank the
0:52:03 dose we can do this slow and low and some people may need more and some people
0:52:06 may need less but the point is is the way it’s being done traditionally where
0:52:09 it’s like you get your script and you walk out of your office and you don’t get
0:52:12 any counseling you don’t get any support this is where people are falling into I
0:52:16 believe the terrible pits of despair so this is where the we’re seeing the
0:52:20 problems and it can be done differently where we’re doing a holistic
0:52:25 comprehensive approach for the patient I was reading a 2024 study by Lindsay Wang
0:52:29 that found diabetic patients taking his MPEC with 50% less likely to develop
0:52:36 bowel cancer compared to those on insulin what does this say and highlight
0:52:40 about a Zempex role in staving of cancer well that’s an interesting study
0:52:45 because insulin is pro-grow so insulin is also a signaling peptide hormone very
0:52:51 much like a GLP1 and it is pro-grow when you give it to someone so someone being
0:52:57 on insulin I believe will inherently potentially make them more vulnerable to
0:53:00 cancer I don’t want to say certainly because I don’t want to scare everybody
0:53:03 because there’s a lot of people out there on insulin but it is a pro-grow
0:53:06 hormone now it’s pro-grow and that we get surges of it after we work out which
0:53:11 is awesome we want that right we want that anabolic response but in your
0:53:14 average person who’s not working out and who’s not really using their insulin
0:53:17 the way they need to they’re already swimming in it due to insulin resistance
0:53:20 and now they’re taking insulin because their pancreas is pooped out that’s a
0:53:25 mess that’s a soup of things we don’t necessarily want happening growing in
0:53:30 the body and so that study looked at insulin versus GLP1 it’s not entirely
0:53:35 fair because it’s not a control it’s not a true control group but they there are
0:53:41 other data sets coming out that haven’t been published yet showing really good
0:53:46 really hopeful and positive impacts on potentially reducing cancer risk and
0:53:50 they’re correlative not causative so we can’t put our finger on it and say these
0:53:55 these reduce cancer but they looked at a you know over a million people that
0:54:00 were type 2 diabetics that were on somaclutide and they found a
0:54:04 significant reduction in different types of cancer that are obesity related in
0:54:08 comparison to the folks who were not taking GLP1s and those were the
0:54:14 the cancers you don’t want the ovarian the pancreatic the colon the types of
0:54:19 cancers that are you know you don’t come back from readily and so that’s very
0:54:22 exciting it’s not getting a lot of play and it’s really really new information
0:54:26 so I’m excited just to watch it but it makes sense to me because these sit on
0:54:29 your immune cells as well there’s GLP1 receptors throughout our entire body
0:54:33 that’s why we’re getting the impacts throughout the entire body and I think
0:54:38 that the impact that it’s having on the overall immunologic milieu of an
0:54:43 individual is potentially very anti-cancer I mean that study that you
0:54:49 cited there I know nothing about as MPEC and GLP1s really but in my even in my
0:54:54 sort of you know chimp brain I go yeah because if they lose weight that’s
0:54:58 likely to get cancer right no that’s totally fair and I think it’s both
0:55:02 because the way that these are working mechanistically in the body and many of
0:55:05 the studies that I’ve looked at are showing results independent of weight
0:55:10 loss even if they don’t lose weight then their cancer risk reduces well they’re
0:55:14 the healing and regenerative and anti-inflammatory impacts are there
0:55:17 regardless of weight loss or not and then you add in weight loss and you add in
0:55:22 insulin sensitivity you add in this this healing of the metabolic dysfunction
0:55:26 and you’re going to significantly reduce risk for everything as well I mean
0:55:29 that’s a really good point actually because if has there has anyone done a
0:55:33 study where they give someone a ZEMPEC and even if they don’t lose weight
0:55:37 inflammation goes down well that’s what the select study this trial show that
0:55:42 that cardiovascular trial I just shared with you they just re-looked at that
0:55:45 information and realized that even independent of weight because that was
0:55:48 the big argument everyone had is well of course the cardiovascular benefits will
0:55:52 stay or will improve because they’re losing weight but they found that even
0:55:55 in those who didn’t lose weight they still had really good cardiovascular
0:55:59 outcomes so yes it that’s what that’s what we’re starting to see and so I think
0:56:02 they need to start looking at these things more readily but they weren’t
0:56:05 right they were just looking at like here’s morbidly obese people and here’s
0:56:08 type 2 diabetics and we’re going to crank up the doses and we’re going to see
0:56:14 what we see but we’re starting to get longitudinal data now so that cancer
0:56:20 one for instance was looking at patient records going way back and so they had
0:56:22 over a million you know people in there that they’re again it’s
0:56:27 correlative it’s not causative but it’s showing trends it’s starting to show
0:56:30 positive trends and so I think that’s what we have to look at and we have to
0:56:35 start to flesh that out what about mental health things like depression and
0:56:41 sort of anxiety these kinds of things you maybe have heard that these are
0:56:47 inducing suicidal ideation and people are you know getting severely depressed on
0:56:53 them and the EU opened a whole research into it and people are very concerned
0:56:58 about this and yet we’ve got studies showing really positive impacts on
0:57:02 depression and anxiety and the thing I will say about that is I’m not saying
0:57:06 that people on Osempic are not having suicidal ideation but that is a little
0:57:11 more nuanced of a conversation because number one when you lose a significant
0:57:16 amount of weight very quickly all kinds of things can go wrong you can end up
0:57:20 with pancreatitis you can end up with gallstones you can end up with severe
0:57:24 depression your fat stores your hormones and so you lose your hormones very
0:57:28 quickly I’ve had patients who got tummy tucks and came in a few months later and
0:57:30 we’re losing their minds because they literally just had all of their
0:57:34 hormonal depots sucked out of their stomach and so there’s concern there
0:57:39 that this rapid weight loss which again I am not a fan of I’m not a fan of doing
0:57:43 it that way but if you drop somebody’s weight significantly you may end up with
0:57:48 a very depressed mood state we’ve also got a bit further to go with that in
0:57:53 that many people are using food as their dopamine source and as their crutch or
0:57:56 as their coping mechanism and I’m not judging I just understand that to be
0:58:00 true you know we all have our advice and if you take that away from someone
0:58:03 because they suddenly don’t want to eat because we’ve crushed their appetite
0:58:06 with too high a dose then I think that we could end up with a very depressed
0:58:11 person in front of us however done correctly and what I’m seeing clinically
0:58:15 is people are having really profound benefits in their anxiety and their
0:58:19 depression and their moods in their cognition I’m seeing neurodivergent
0:58:25 folks taking it who are becoming much more functional in the in their everyday
0:58:30 day to day I’m seeing people who are more of a hermit who don’t want to go out in
0:58:35 the world suddenly venturing out being more social so there is an impact on
0:58:38 the brain and I think it’s the anti-inflammatory mechanism I think
0:58:43 it’s the dopenergic system the dopamine pathways being impacted and again if
0:58:47 we’re not cranking the dose up I think that we can use these effectively to
0:58:52 bolster mood to improve cognition to improve brain clarity and all of that
0:58:55 leads you know an inflamed brain is a depressed brain at the end of the day
0:58:59 we have to get that point really clear depression is a brain inflammation
0:59:04 issue you’ve mentioned sort of sexual health a few times and fertility in
0:59:08 passing when we’re talking about a zempec women’s sexual health male
0:59:15 fertility what is the the impact in your view of and it is then pecking to
0:59:22 mention on these kinds of things well the fertility conversation is really
0:59:27 daunting and it’s kind of a long one but we are looking we are a few generations
0:59:35 into a major fertility crisis and they say what is it by 2100 2100 by 2000 by
0:59:40 2100 97% of countries in the world will not be reproducing at a rate to
0:59:45 repopulate themselves we are looking at a population crisis by 20 by the mid
0:59:51 2040s they say sperm rates are going to be at zero and again that’s
0:59:56 multifactorial but my firm belief at the root of this is metabolic dysfunction
1:00:00 I I firmly believe that metabolic dysfunction is probably the biggest
1:00:04 driver if I could press a button and fix it I would put my finger on the
1:00:11 metabolic dysfunction button and GLP ones heal metabolic dysfunction and so
1:00:15 we’re seeing reversal in PCOS which is probably one of the number one drivers
1:00:19 of infertility in young women period which is really at the end of the day
1:00:24 just metabolic dysfunction it’s just presenting in women with high androgens
1:00:28 the the clinical picture PCOS isn’t doesn’t always involve cysts on the
1:00:31 ovaries it’s just this I don’t even know why it’s called that anymore it’s a
1:00:35 clinical picture where they have metabolic dysfunction they have high
1:00:39 testosterone they have low progesterone their estrogen gets converted readily
1:00:44 into testosterone they end up with hair growth they end up infertile it’s a
1:00:47 disaster many many young women many women in your age cohort have this
1:00:53 condition many women in your many couples in your age cohort are not able to
1:00:57 get pregnant without IVF at this point people are not getting pregnant I don’t
1:01:01 know how old are you 31 yes people in their 30s are not getting pregnant and
1:01:05 when I asked my friends in their 30s all over the world I say what’s like how’s
1:01:08 how’s the pregnancy going with like how how’s it going with your friends and
1:01:12 they’re like everybody’s on IVF it’s I don’t know what you’re hearing but it
1:01:16 like that’s crazy to me that 30 year olds are having to do IVF healthy-
1:01:22 looking 30 year olds are having to do IVF so we’ve got sperm issues and we’ve
1:01:26 got egg issues it’s both it’s not just the female’s fault it’s not just the
1:01:30 male’s issue we’ve got sperm health we’ve got sperm volume we’ve got sperm
1:01:34 motility issues we’ve got metabolic dysfunction in both groups and what
1:01:40 happens when we do have a successful pregnancy is that that offspring is
1:01:45 being epigenetically flagged if the mother is obese and dealing with
1:01:51 metabolic dysfunction and even if the father is that fetus ends up bathed in
1:01:56 insulin in utero and they come out of each epigenetically marked for much
1:02:00 more severe risk of metabolic dysfunction and obesity in their own
1:02:04 lives and that cycle just goes into perpetuity that’s where we’re at we’re
1:02:09 several generations into this as a species and so I’m worried like I’m
1:02:13 legitimately I joke that humans are going extinct but it’s not funny and I
1:02:17 think it’s really happening and I I do believe it will happen in the next few
1:02:21 generations if we don’t write this ship and at the root of it is this overarching
1:02:28 metabolic dysfunction 2018 data out of the U.S. that was published in 2021 showed
1:02:35 that only 6.8% of U.S. adults are metabolically healthy 6.8 so that’s
1:02:42 93 94% of U.S. adults are cardiometabolically busted that’s and that
1:02:51 was pre-lockdowns why that’s a great question you talked about PCOS and this
1:02:55 sort of infertility crisis and then you talked about it being about metabolic
1:02:58 dysfunction yeah where is the metabolic dysfunction coming from what is the
1:03:02 thing furthest upstream if we were to attack it at its source yeah the food
1:03:07 supply was significantly adulterated in the past few generations so it’s
1:03:10 starting with my parents the boomers you know they got their convenient food
1:03:15 they’re everything was about convenience that’s when we got you know
1:03:21 disposable diapers and fancy microwaves and dishwashers and all that jazz well
1:03:26 food became very convenient as well in the 90s I watched this happen in my
1:03:31 lifetime in the 90s the food supply was significantly adulterated and
1:03:36 terrifyingly so and they found the bliss point right the perfect emulsion of
1:03:41 sugar fat and salt to hit those neurotransmitters in the brain to make
1:03:47 you want to come back for more toxicity is a huge issue I believe toxicity in
1:03:52 general not just environmental toxicity but it’s the chemicals in our food what
1:03:56 we’re doing to ourselves so many young women today are bathing themselves in
1:04:00 toxic chemicals through their beauty habits I mean the nails and the hair and
1:04:05 the skincare and it’s it’s really really severe so it’s this sort of
1:04:09 multifactorial thing humans are actually eating the same amount or less
1:04:14 calories than they were 30 years ago it’s not the caloric intake it’s not
1:04:18 that people are sloths and they’re lazy and they need to do better it’s that we
1:04:23 are swimming in a toxic soup we are eating a very adulterated mineral
1:04:28 deficient protein deficient chemical shit storm of a food supply and then you
1:04:33 throw in the mass I mean to be totally honest with you the a massive uptick in
1:04:38 vaccines in infants when they come out I mean that’s a whole different ball game
1:04:41 than it was even when my daughter was an infant it’s significantly different than
1:04:46 when I was an infant so we’ve just we’ve got a lot of things coming at these
1:04:50 young people and it culminates you know and it adds up and I think people don’t
1:04:55 realize we have a toxic bucket we all have an individual toxic bucket and that
1:04:59 bucket will become full for whatever reason maybe we’ve got mold exposure
1:05:02 maybe we’ve got too much stress it’s it’s multifactorial but that bucket will
1:05:08 fill up and overflow and metabolic dysfunction is a result of that and
1:05:13 also a driver of that so it’s it’s very hard to put my finger on why or the
1:05:17 chicken and egg what’s what’s leading to what I know that there’s things we can
1:05:21 do that are non-negotiable to help write the ship as best we can that have
1:05:25 nothing to do with drugs and have nothing to do with peptides and I’ve been
1:05:29 talking about this for decades we must be strength training and optimizing our
1:05:34 muscle we must be walking every day like human beings do humans were made to
1:05:38 walk and lift heavy shit right we are meant to be in community we’re not
1:05:42 meant to be isolated we’re meant to be around others we are meant to share our
1:05:46 microbiomes we are meant to have healthy microbiomes not these super
1:05:51 sterilized microbiomes the abundance of microbiome disruption from all the
1:05:57 antibiotics I mean that alone causes lifelong issues for people and so you
1:06:03 stack all this up and people are sitting at home they’re alone loneliness is an
1:06:07 epidemic they’re eating food that comes from uber eats or I don’t know what you
1:06:11 have here but they’re ordering in they’re eating processed foods for most
1:06:15 meals they’re not getting out here in London I’m so happy everybody’s walking
1:06:18 but back in the US everyone just drives everywhere maybe in New York they walk
1:06:22 but any anywhere else you go you know it’s like get up go from the bed to the
1:06:28 couch to the car to the desk back to the car to the couch to the bed people are
1:06:32 not exercising people are not paying attention to nutritionally dense food
1:06:36 they’re not getting sunlight they’re not in community I think COVID really
1:06:39 squelched community just in so many different ways you know a lot of
1:06:44 churches are sort of disbanding communities are disbanding they shut
1:06:49 the gyms down so there’s just all of these factors that culminate into a human
1:06:54 being that isn’t a healthy human being just on that point of PCOS if I was a
1:06:59 young woman I was 31 years old and I came to you with PCOS polycystic ovary
1:07:03 syndrome and it was impacting my fertility you could see I had the you
1:07:07 know high testosterone levels I had slightly hairy arms I was maybe put in
1:07:12 some way what would you aim at what would you do I would prioritize protein
1:07:17 first of all yeah I would go for 30 grams of protein three meals a day as best
1:07:21 that you can I don’t even care if it’s grass-fed fancy protein I just want to
1:07:25 be eating animal protein if they will do it I want them immediately cutting out
1:07:29 as many of the chemicals that are applying to their skin and their bodies
1:07:32 so they’re not getting their hair done they’re not shooting the Botox they’re
1:07:36 not putting the nails on they’re not I mean it’s just a chemical the what’s
1:07:38 coming at young women is crazy when it comes to their beauty routines at this
1:07:43 point I would have them walking three times a day for ten minutes each so three
1:07:48 ten minute walks outside preferably getting up and seeing the sunlight so we
1:07:52 set the circadian rhythm so it’s really important that you get up and outside
1:07:55 first thing in the morning to get natural sunlight in your eyes and it’s
1:07:59 really important that you see it in the afternoon as the Sun is waning that sort
1:08:04 of golden hour you know as the Sun starts to wane in the sky and the sky
1:08:09 gets golden go outside then that really helps you asleep sleep is critical cut
1:08:14 the blue light put the you know amber blue light blockers on at night stop
1:08:18 staring at the phone in the TV until 10 o’clock at night get that shit out of
1:08:21 there because that is jacking up people’s rhythm which is jacking up their
1:08:27 fertility and their hormones strength training is non-negotiable we have to
1:08:30 protect our muscle we have to build it I’m a skinny girl and I lift more than
1:08:35 you would believe and I don’t look at I can’t hold it but I try so really
1:08:40 optimizing muscle that alone would be a game changer like if they didn’t even
1:08:44 cut out I wouldn’t even pull foods away from them I would just say focus on
1:08:47 eating getting the protein in and the other foods will start to fall away and
1:08:50 when you start to do all the other things that are good for you you start to
1:08:54 make better choices when you feel better you do better I have reversed so much
1:08:57 PCOS and women like that next I would add in some progesterone which is
1:09:00 available over-the-counter but obviously do that under the care of someone who
1:09:03 knows what they’re doing so you don’t take too much progesterone but
1:09:06 progesterone’s a very important player in there it’s actually a neuro hormone
1:09:11 it’s it’s very safe and effective and I would get them eating as much of a
1:09:16 whole food diet as I could could you can you reverse PCOS yeah yeah I mean
1:09:23 they’re so you know genetics loads the gun and environment pulls the trigger so
1:09:27 they came out with some bad epigenetic flags but that doesn’t mean that that’s
1:09:32 their fate none of us it is not my fate to die a miserable death from psoriatic
1:09:36 arthritis I will do everything I can to make sure I keep that at bay and that’s
1:09:40 something that medical doctors don’t tell you you go in they say you have
1:09:46 this there’s nothing we can do and I’m like could I take a multivitamin could
1:09:49 might is changing my diet gonna do anything and back when I was growing up
1:09:53 there was like there’s nothing you can do good luck at least now doctors are
1:09:56 starting to get a little more savvy and realizing it’s more nuanced and I’m
1:09:59 starting to see the professions come together more and realize like diet
1:10:02 actually matters and I’m starting to see it in the headlines of the medical
1:10:06 journals like diet actually matters lifestyle matters light matters you know
1:10:12 but all of these things what I tell patients is I’m not gonna cure you you
1:10:15 are genetically and epigenetically primed but we’re gonna try to keep that
1:10:20 as quiet as possible we’re gonna try to keep you optimized so that this over
1:10:24 here doesn’t rear its ugly head but you know throw in a bad viral infection or
1:10:29 throwing a big stressor or throw in you know something major like a birth
1:10:33 childbirth and you might get off kilter again but that doesn’t mean you don’t
1:10:38 have all the control in the world to help mitigate that I have to say you know
1:10:42 as someone that comes from I’m gonna try and pronounce it again nature medicine
1:10:48 it is quite surprising to hear you talk about micro dosing on a zempec I know
1:10:52 because you know I think naturopathic medicine you’d imagine they were very
1:10:57 much against micro dosing or dosing any sort of chemical pharmaceutical right
1:11:01 so how do you square the circle there because it’s a peptide and it’s been
1:11:05 appropriated by the pharmaceutical industry because of its delivery system
1:11:09 but there’s many other peptides that are available over the counter for
1:11:14 instance in supplement form like BPC 157 which is a regenerative peptide it’s
1:11:17 also anti-inflammatory all of these peptides generally are regenerative
1:11:21 anti-inflammatory and healing they all just kind of have their special skill
1:11:26 set so we’ve got a variety of different peptides that were pulled by the FDA
1:11:29 because they work is my opinion but we also have ones that are available over
1:11:33 the counter that are in sprays that are in pills if you go get hurt you can
1:11:37 order them online it’s legal I’m not talking any black market this these are
1:11:41 reputable companies in a supplement form and you can induce phenomenal healing
1:11:44 in your body and these are available people just don’t know about them and
1:11:47 they don’t know how to use them and they are a bit expensive this is just
1:11:51 another peptide it just happens to be held over here and it’s being used in a
1:11:57 way by brand name pharmaceutical big pharma companies in a way that I just
1:12:01 don’t think is appropriate for peptide use you’ve used that phrase done
1:12:05 correctly a few times when you’re talking about the micro dosing of a
1:12:07 zempec and you’ve also highlighted there but also previously in this
1:12:14 conversation that people are using it wrong so I all using it in too high of a
1:12:18 dose so I am I brought with me today some little science lab which I’ve got over
1:12:21 there in the corner because I would like you to show me when we talk about
1:12:25 micro dosing a what micro dosing is yeah as a term what does that mean but
1:12:30 also could you show me the comparative difference in how you would and you are
1:12:35 giving your patients as MPEC what dose you’re giving them comparatively yes to
1:12:39 how it’s typically being administered in what dosage for the sort of weight loss
1:12:43 effects that we’ve talked about and that most people know it for sure yeah
1:12:50 okay so let me bring over the zempec okay so this is what they start people on
1:12:56 and then every month every four weeks in the traditional model with the brand
1:13:02 names like ozempic and we gov and manjaro they double this is this would
1:13:06 be specifically for some aclytide okay so let me back up here just I’ve got my
1:13:09 and some with you so typically when they administer a zempec and some
1:13:15 maglots maglotide they do it in a pen which you kind of self-inject which is
1:13:20 that a controlled dose yes so you can’t give yourself whatever quantity you like
1:13:26 right kind of like a set dose you go and it injects into you yep okay okay so
1:13:30 they start them here with that much in it so for people that I can’t see because
1:13:35 they’re listening audio it’s point two five milligrams okay and then every month
1:13:41 they double the dose about over 16 weeks they double the dose until they get
1:13:47 folks generally now smart docs will stop people where they need to stop but the
1:13:55 standard is to get them up to about here per week per month I’m sorry per week
1:13:59 yes per week they do this per week they get them up to here this is what the
1:14:04 studies have been done on and so this is how it’s traditionally dosed and if
1:14:09 you’re severely diabetic or obese I could see the rationale I’m arguing I
1:14:12 still don’t think that’s necessary when you have the appropriate lifestyle
1:14:16 interventions okay if you’re treating someone comprehensively using other
1:14:21 peptides using hormones getting people to do the healthy lifestyle changes I
1:14:26 don’t think this is necessary and I think this leads to a very high risk for
1:14:31 side effects so we went from was it point two five to two point five basically so
1:14:36 ten times more yeah over the space of X matter weeks 16 weeks 16 weeks okay so
1:14:43 they 10x the dosage over 16 weeks yep which looks like which is a lot so you’re
1:14:48 taking that much injected into you self-injected every week every week okay
1:14:51 and you do that you’re theoretically supposed to be on that dosage forever
1:14:55 yes and they don’t ever stop they don’t take breaks they’re not concerned about
1:14:59 receptor sensitivity it’s just they just go it’s just you’re on this and you’re
1:15:03 on it for life now some there are really good weight loss docs out there and
1:15:06 they are helping their patients get off of them and actually the more recent
1:15:09 data is showing that when folks are exercising just it doesn’t even matter
1:15:14 what kind of exercise when folks are exercising in addition to they can come
1:15:18 off more successfully and maintain the weight loss so that’s promising however
1:15:22 my argument is in somebody who’s metabolically optimized now this isn’t
1:15:25 everyone this isn’t your severely obese patient but in somebody who’s
1:15:31 metabolically optimized I give them a fraction of this and that differs by
1:15:34 person but I actually have to use an insulin syringe so that I can do a
1:15:39 fraction of the starting dose and I may never elevate it I may never ramp it up
1:15:45 so compared to the 2.5 milligrams in there you’re giving out how much I’m
1:15:50 giving a fraction of 0.25 I’m giving a fraction of this so you might be giving
1:15:56 0.0 it depends it depends on the patient and without getting into detail
1:16:00 because whenever I do people start playing with their dosage themselves and
1:16:04 I’ve heard seeing crazy things in the comment section of my posts on
1:16:08 Instagram so I don’t want to tell people exactly how to dose but it depends it
1:16:11 depends on what they’re going and this is a bigger conversation because I don’t
1:16:16 ever do somaclutide as a monotherapy I never do it by itself I never just crank
1:16:21 people on somaclutide and hope for the best if that is the only geo if I’m
1:16:25 sorry if that’s the only peptide they’re using they likely will have to keep
1:16:30 going up and so I have one patient who is obese and has some weight to lose and
1:16:36 I have taken nine months to get them to here which is roughly one one milligram
1:16:40 that’s one milligram so he’s on one milligram and I really don’t want to
1:16:45 raise it I really want him doing more of the lifestyle interventions to start to
1:16:48 heal the metabolism as well so it’s a multi-pronged approach I’m trying to
1:16:52 heal the metabolism at the end of the day this is one tool but there are other
1:16:58 tools but this is a pretty potent tool so in the case of someone that is
1:17:02 micro dosing how frequently are they taking that small dose in the small sort
1:17:06 of petri dish in front of you it depends so give me give me a case study of the
1:17:11 typical person well it depends on what I’m going for what my short-term goals
1:17:17 are what my long-term goals are so for myself I was having to do a fraction of
1:17:23 this droplet here not this this once a week as people heal and improve they’re
1:17:27 able to space that out some people can space it out two weeks so some people
1:17:30 are dosing every two weeks some people are dosing once a month it really
1:17:34 depends some people are there’s a lot of folks thinking they’re micro dosing but
1:17:37 they’re actually just barely going below that point two five they’re still
1:17:40 almost right at it so they’re still doing a large percentage of this and that’s
1:17:44 not really micro dosing but they’re getting results and so my goal is always
1:17:49 just to dose people just below symptoms I never want them symptomatic I never
1:17:52 want them saying I’m nauseous or throwing up or having any of that there’s no
1:17:55 need for any of that I want them just below symptoms and I want them
1:18:00 continually improving and getting the results I’m looking for that might be
1:18:04 lowering of blood pressure it might be improvement in mood it might be you know
1:18:08 continuing clearing of their skin lesions it depends on what we’re going
1:18:13 for and then my goal is to cycle this so I will try to get them off for as long
1:18:17 as I can and I will try to try to take breaks for as long as I can because I
1:18:20 want the cells to resensitize so that might be like I said two weeks it might
1:18:25 be a month some folks might just do this a couple times a year they may not be
1:18:29 on it continuously they might just do what we call a cycle this is you might
1:18:32 be familiar with this if you’ve interviewed anyone on testosterone
1:18:36 therapy often it’s a cycle and so they’ll do a few months maybe 90 days on and
1:18:40 then they’ll take some time off it totally depends on the patient and what
1:18:43 I’m going for though and it depends on again what am I trying to accomplish
1:18:47 short-term and what am I trying to accomplish long-term and how compliant
1:18:49 are they being with the rest of the treatment plan so give me a case study
1:18:54 then of someone who has microdosed with you successfully and they’ve gone from
1:19:00 ill health in some form to healthy so my mom is a great example she started on a
1:19:04 tiny little bit because I said she’s older and she’s a bit frail and she was
1:19:09 going into it with gut issues already so a very tiny little bit she actually
1:19:13 ramped herself up I’m not sure why she ramped herself up a bit she got a bit
1:19:16 symptomatic so she was still at well below this
1:19:21 droplet amount and I’ve recently it’s been maybe nine months I’ve recently
1:19:27 brought her back down to a droplet and I’m trying to keep her there and she’s
1:19:30 still doing it once a week and we’re starting to play with how long can she
1:19:33 go off of it before we start to see symptoms I don’t want the symptoms to
1:19:37 come back full bore because then we know tissue destruction is happening I’m
1:19:41 trying to heal people in the process of treating people if it makes sense I want
1:19:44 both to happen but she also needs to be compliant with all the things and so
1:19:49 something I’m hearing about a lot which is a great case example is many of my
1:19:52 colleagues who I have a program where I teach people how to do this and many of
1:19:55 my colleagues are thinking they’re microdosing and they’re not and then
1:19:59 they start calling me and they’re like they’re either running into symptoms or
1:20:02 they’re hitting a wall and their patients are plateauing they say it’s not
1:20:05 working anymore I’m like well what are you going for if they’re going for weight
1:20:09 loss they are gonna plateau if they’re not because they haven’t implemented the
1:20:11 strength training yet or they haven’t implemented maybe some of the other
1:20:15 bioidentical hormone replacement or whatever it may be you know they’re not
1:20:19 doing the they’re not taking care of all of it holistically and so they’re
1:20:24 running into some barriers what is what is the role it’s playing if you’re
1:20:27 doing it at such low doses what is the role that it would play for someone with
1:20:32 for example chronic pain or some form of inflammation in their body well why
1:20:37 is such a small dose in important in the bigger picture you described there of
1:20:40 getting their health back in shape is it because if you said earlier about the
1:20:44 brain fog and getting them to a state where they can make better decisions I
1:20:48 think it’s actually also in the brain so GLP one is secreted in the brain
1:20:52 something that most people think is that it’s secreted in the gut and then it
1:20:55 makes its way to the brain there’s actually different regions of the brain
1:20:59 where GLP one is produced and there’s receptors all over the brain to receive
1:21:03 the GLP one so I think something very important is happening in the brain that
1:21:09 we really are only just starting to understand and I believe that the
1:21:13 downstream impacts of that of healing that like I said at the beginning if we
1:21:18 heal the brain we heal the immune system we heal everything downstream and so I’m
1:21:23 really trying to have a cognitive impact and so that’s it becomes more
1:21:26 critical than to do all the lifestyle interventions that reduce neuro
1:21:29 inflammation we want to make sure they’re taking supplements that are
1:21:33 supportive for brain health we want to make sure that their lifestyle habits
1:21:36 are supportive to brain health they’re not continuing to drink a bunch of
1:21:39 alcohol although this makes most people not want to drink even at tiny doses
1:21:43 most people just want to stop drinking it’s really phenomenal they want to kind
1:21:47 of stop doing all their bad habits they want to stop chronically shopping they
1:21:51 want to stop all the dopamine-chasing habits that they have which is is now
1:21:55 if you go too high though you start to impact reward systems and I can see where
1:22:00 they start to get depressed so I’m trying to have a positive healing
1:22:04 regenerative impact on the brain and the immune system to ultimately heal them
1:22:08 up and hopefully I can take them off of them or maybe they might have to revisit
1:22:11 it if there’s a flare if something comes up in their life that sort of set like I
1:22:14 said you kind of get set back over the edge we might have to bring it on board
1:22:19 for a minute but I’m ultimately doing an initial healing phase and then I’m
1:22:23 doing a maintenance phase you’ve mentioned alcoholism there and you
1:22:29 mentioned your husband earlier as well how well is that research to show the
1:22:33 impact that it has on addictions they’re studying it but people want to stop
1:22:37 smoking people want to stop doing cocaine people want to stop doing all
1:22:42 kinds of things and it’s very interesting and they Johan actually talks
1:22:45 about this in his book and he does a nice job of breaking down the science
1:22:51 there on it they looked at rats and they thought okay well if this is just
1:22:55 crushing the reward system then it would crush all the reward systems but it’s
1:22:59 not crushing libido for people and it’s not crushing some of the other reward
1:23:03 seeking behaviors it just seems to be crushing many of the ones that are
1:23:08 pathologic or not so great for our health and long run and he actually talks
1:23:13 about a study that I’ve read as well where they took rats and they gave them
1:23:17 sort of that like yummy emulsion of that sweet sugar salty deliciousness and
1:23:21 then they gave them rat chow and when they put them on somaculotide they
1:23:25 stopped seeking out the yummy devils I mean that’s the that emulsion is what
1:23:31 makes you become very metabolically you know compromised and they still ate the
1:23:34 rat chow they still went for they went for the healthy food I don’t know how
1:23:39 healthy rat chow is that’s debatable but they went for the more nutritionally
1:23:43 dense food and they actually stopped seeking out the pleasure food and I’m
1:23:45 seeing that across the board with all kinds of behaviors I got a message from
1:23:50 a lady she said I had no idea I had such a severe online shopping habit like I
1:23:54 would just fill the cart up and purchase and then she started filling the cart up
1:23:57 and not purchasing and now she’s not even online shopping she’s not even like
1:24:01 going in to make the to have the experience it’s really interesting what’s
1:24:05 going on in the brain there in your opinion it plays on the hypothalamic
1:24:10 pituitary axis to some degree and it is impacting dopaminergic pathways and at
1:24:15 the end of the day the dopaminergic pathways are dopamine seeking system is
1:24:21 in a simplistic way to describe it as our addiction system so we chase that
1:24:25 dopamine dragon that dopamine dragon might be sex it might be gambling it
1:24:28 might be cigarettes it might be whatever it is whatever that thing is that gives
1:24:33 us that hit and interestingly about dopamine and why it becomes such a
1:24:37 process I mean I think a lot of it is these cell phones it’s this quick we’ve
1:24:40 got a very quick reward system society you know back when I was a kid we had to
1:24:44 like wait outside in the freezing cold all night to buy concert tickets and now
1:24:47 you guys are like well I’m just gonna buy whatever I can afford to get the best
1:24:51 seat it’s a very different world you know and everything’s right at our
1:24:54 fingertips and it’s very it’s very quick response and so our dopamine
1:24:59 circuitry is really screwed up dopamine is healthiest and signaling best when
1:25:04 we’re seeking out the challenge it’s not when we get to the it’s not when we
1:25:08 win have you ever wanted something really badly and then you succeeded and
1:25:13 you got there and you were like and just not feel it’s just wasn’t what I it’s
1:25:17 because it was the journey there it was the conquest of getting the thing of
1:25:21 achieving the goal that’s what gave you the dopamine it’s not as much getting
1:25:24 the thing at the end of the day and this is playing somewhere in that system and
1:25:29 people are just not having the rewards seeking behavior as they were I have had
1:25:34 so many people reach out to me and say when it came to food in particular this
1:25:39 must be what normal people’s brains feel like I don’t wake up obsessed thinking
1:25:42 about food I don’t go throughout my day obsessed thinking about food I can
1:25:45 actually think about other things but really what we’re saying here then is
1:25:52 that hunger is much more than a desire for food hunger is a much broader sort
1:25:56 of psychological phenomenon that’s about dopamine and reward and all these
1:26:02 things so when we attack so GLP ones role isn’t just in hunger it’s in this
1:26:06 bigger psychological sort of incentive structure either was weird because as
1:26:09 you’re saying that this morning I didn’t eat right because I didn’t have
1:26:12 breakfast and I didn’t have lunch because I was doing my annual health check so
1:26:16 they say you got a fast beforehand so I didn’t have anything and my first meal
1:26:20 per se was about 2 p.m. you can see my little jab in my own little can you let
1:26:27 them put them on and I got to about 3 p.m. and I hadn’t eaten and I have this
1:26:31 drawer in my car that you can’t we typically pick up guests in and it’s got
1:26:35 some like less healthy snacks in I try and stay out of it but because I hadn’t
1:26:38 eaten for some reason I was like I need to go and eat food I need to go and eat
1:26:43 the sugary stuff so as you were talking I was thinking is the administration of
1:26:48 GLP one and as MPEG just bringing down that noise a little bit to the point
1:26:53 that I’d no longer want the sugary snack drawer because I was thinking to
1:26:57 myself this morning if I had if that was the start of the day when I was less
1:27:01 hungry I wouldn’t have been thinking about that snack drawer but because the
1:27:06 day went on and I became more hungrier I had a greater pull-on dopamine so
1:27:10 there’s people living tip you know their everyday lives with this kind of greater
1:27:14 demand for dopamine for whatever reason and it’s coming from gambling or
1:27:17 porn addiction or what will shopping addiction and what GLP one is doing is
1:27:22 it’s just bringing not just the fit that I need food that that the hunger down
1:27:26 it’s bringing the sort of dopamine pathway down in terms of volume it’s
1:27:29 quieting the noise that’s a really good way to put it and that’s how people
1:27:33 describe it as they call it the you know the the food noise or the hedonic
1:27:37 urges it it quiets the noise down and that’s why I was saying earlier that it
1:27:41 gives people this wonderful window of opportunity to be back in the driver’s
1:27:46 seat they sometimes for the first time in their life have full control over what
1:27:48 they’re choosing to eat when they’re choosing to eat what they’re putting in
1:27:52 their mouth and some people didn’t have that control before and it’s not just
1:27:55 dopamine we’ve got leptin we’ve got ghrelin we’ve got these different
1:28:00 appetite they’re also peptide signaling hormones and they all play
1:28:06 together and they don’t play well if GLP one’s not in there so if leptin is
1:28:09 happening and ghrelin is happening and we can go into the details of that if
1:28:14 you want if GLP one’s not there the orchestra doesn’t work and there’s a
1:28:17 lot of folks sitting around with leptin resistance insulin resistance they’re
1:28:22 not responding to ghrelin this even the cell receptors getting to the edge of
1:28:27 the membrane is sometimes GLP one contingent and so my argument is that
1:28:33 sometimes the tiniest little amount might be what that person needs to kind of
1:28:38 harmonize the orchestra maybe you know we can’t have and this is the other
1:28:41 reason I don’t love it in monotherapy imagine a jazz band and you just had one
1:28:45 big bass drum that would be ridiculous it would sound terrible right like the
1:28:49 nuance in the jazz drummer is what makes jazz so cool a lot of folks are using
1:28:56 this at this dose right this huge dose and that’s the big old bass drum and
1:29:02 they’re just crushing the whole brain circuitry to suppress hunger period and
1:29:05 they’re ending up with all these downstream side effects which are not
1:29:10 fun my argument is if we just harmonize the orchestra but sometimes we need a
1:29:13 little estrogen or a little progesterone or we need a little bit of this or that
1:29:16 we need to do some lifestyle things to get the leptin resistance to reset and
1:29:19 the insulin resistance to reset but we might need a little bit of GLP one on
1:29:26 board every single time you eat you have an opportunity to improve your health
1:29:29 and that’s why I love Zoe because Zoe helps me to make the smartest food
1:29:34 choices for me and my body and as you guys will know by now Zoe is a sponsor
1:29:38 of this podcast and I’m an investor in the company and if you haven’t tried Zoe
1:29:42 I highly recommend you do because Zoe combines my health data with Zoe’s
1:29:47 world-class science and using those two things Zoe guides me to better health
1:29:51 every single time I make a food choice and eat which means that I have more
1:29:55 energy better sleep better mood and I’m less hungry and the most important thing
1:29:59 is Zoe actually works it’s backed by their recent clinical trial something
1:30:03 called the method study which is the gold standard of scientific research I
1:30:07 started Zoe just over a year ago now and I’ve been able to track my progress
1:30:11 week after week so I can learn how to be even smarter the following week and if
1:30:15 you haven’t joined Zoe I’m giving you 10% off when you join Zoe now just use
1:30:21 the code CEO 10 check out what if someone says that we haven’t got clinical
1:30:27 studies yet to prove that micro dosing is safe over the long term and it could
1:30:30 be doing long-term damage because these compounds have only been around for a
1:30:35 while a couple of years now and in terms of people really using them on mass well
1:30:40 I think we would be far more concerned with high doses and that’s what most
1:30:44 people are on or on high doses and we’re really not seeing the safety signal
1:30:47 blowing off the way that people are concerned about in fact we’re seeing the
1:30:51 opposite of that some really good data has come out refuting many of the studies
1:30:56 that were so concerning in the past few months even and some of it’s just being
1:31:00 presented at different conferences so it’s not being published yet but I keep
1:31:04 up with all of it and it’s very exciting we’re not seeing a signal on
1:31:09 pancreatitis we’re not seeing bowel obstruction gastroparesis I think it’s
1:31:14 fair to say that the highest risk group for gastroparesis is type 2 diabetics
1:31:18 it’s because they are sugaring up their vagus nerve the high blood sugar is
1:31:23 actually destroying the vagus nerve which is causing low-grade gastroparesis so
1:31:25 they’re already sitting on the edge of it in many cases and then they’re being
1:31:29 cranked into these crazy high doses and getting thrown over the edge a real
1:31:35 concern is biliary disease so gallstones when you go on a very severely
1:31:40 calorically restricted diet your bile sludges up in your gallbladder so gall
1:31:45 bladder is already very often compromised in an obese individual and it’s
1:31:48 already sludgy and it maybe already has some stones forming and then they go on
1:31:53 a caloric restriction that lack of food going through the digestive tract will
1:31:58 cause the bile to sludge up they’ll throw a stone into the pancreas the number
1:32:03 one cause of pancreatitis is fatty pancreas which people with metabolic
1:32:08 dysfunction already have then the second cause is a gallstone and the third
1:32:14 cause really is excessive severe weight loss done too quickly so we’re taking
1:32:18 people and thrusting them up on these high doses they’re often already sitting
1:32:21 on the edge of many of these conditions and then they’re getting thrown over the
1:32:25 edge it’s like well yeah no wonder when I started looking at the terrible side
1:32:29 effects I was like well of course I mean anybody who is severely diabetic or
1:32:34 severely obese is already sitting on the edge of that and so my argument is why
1:32:37 are we throwing people on these high doses and sending them over the edge I
1:32:41 don’t think taking a tiny amount of something is nearly as concerning as
1:32:47 the high doses but the rates that you’re hearing in the media are not the
1:32:49 rates that are showing up in the studies even of these terrible side effects I
1:32:53 just mentioned I have always believed that there’s no such thing as a free
1:32:57 lunch that’s fair in life and you know whenever someone tells me that something
1:33:05 is good for me it always comes with a cost you know like if that just seems to
1:33:08 be the way that life works and I like that life has that balance to it where
1:33:11 there is no you know anything that’s worthwhile whether it’s starting a
1:33:16 business having a great marriage or relationship raising kids right there’s
1:33:21 so much of an upside and there’s so much of a cost you know and so as it relates
1:33:25 to micro dosing is MPEG my brain is going there’s got to be a cost
1:33:30 if there is any reward there has got to be a cost that’s fair we have to think
1:33:33 about the risk-reward ratio and that’s something that we don’t talk about in
1:33:40 medicine I think COVID really showed that you know you have the risk of COVID the
1:33:44 real risk of COVID whatever that looked like depending on the scale of
1:33:49 susceptibility you had for poor outcomes so if you were 65 or older you were in
1:33:53 poor health there was a real risk and then you have the reward we have to look
1:33:59 at what lockdowns did we have to I mean 146 percent increased risk of suicidal
1:34:03 ideation all kinds of I mean I get the stats on that I don’t even want to that
1:34:07 like makes me sick when I start thinking about what happened I was just
1:34:09 driving over here and the Uber driver was telling me how nobody goes to church
1:34:12 anymore and all the bars are the pubs are closing because the culture the pub
1:34:15 culture is going away not because of drinking but because of just people
1:34:19 joint gathering and community you know like he said it was the COVID was the
1:34:24 end of so much of London that he saw and he’s been driving for in some form or
1:34:28 another for 15 years through London and so we have to look at risk-reward ratio
1:34:34 and the risk of walking around in a chronically inflamed state for somebody
1:34:37 who say has psoriatic arthritis I have thought about this and I’m like you know
1:34:43 what the risk that I’m seeing in the data from high doses of this is probably
1:34:47 not nearly the risk of a tiny dose of it and it certainly is better than the
1:34:51 clinical outcomes of walking around with raging psoriatic arthritis for the
1:34:59 next 30 40 years which is dementia my spine fusing lack of movement muscle
1:35:07 wasting chronic pain so on and so forth the real risk of obesity is tremendous
1:35:12 and something that a lot of people don’t appreciate is when we start to gain
1:35:16 weight in middle age that’s a low-grade insulin resistance happening and so a
1:35:20 woman will gain you know somewhere between 45 and 50 she might gain 10
1:35:24 pounds okay we get a little thicker as we get a little older okay maybe the
1:35:28 next five years she gains another 10 pounds and we just sort of accept it as
1:35:32 a society like all our moms kind of get bigger right all moms just get bigger and
1:35:35 they all end up looking like they you know the whole the moms the grandmas
1:35:41 everyone ends up in my family round by the end of it well now my family
1:35:45 starting to drop dead of heart attacks and they’re all on lifestyle medications
1:35:48 they’re on statins and blood pressure medications and all of these things and
1:35:52 my thinking is what if that process never even started what if I was able to
1:35:56 intervene with not just GLP ones but all the other tools I had available to me
1:35:59 that I didn’t have when they started I wasn’t out of school yet I didn’t know
1:36:04 what I know now what if I was able to intervene and give them decades more of
1:36:07 a high quality life and that’s what longevity medicine is that’s what
1:36:11 hormones are that’s what bioidentical hormone replacement is and what these
1:36:15 other peptides are that we’ve been using for a long time in clinical decades in
1:36:20 clinical practice and I don’t know if you you probably don’t but the women’s
1:36:26 health initiative 20 plus years ago came out with data showing estrogen and
1:36:30 progesterone replacement therapy is dangerous and all women were immediately
1:36:35 ceased doctors got scared everybody got taken off their hormones we just
1:36:40 destroyed an entire generation of women over the past 20 years doctors that
1:36:44 were smart like myself and my colleagues we read the data and we realized that
1:36:48 they were giving them progestin and not progesterone and there was nothing
1:36:51 unsafe about what they were getting and so we kept everybody on their hormones
1:36:55 and I’m like well here’s informed consent I would tell the patients this is the
1:36:58 data this is what we’re gonna do they agreed or didn’t agree that’s called
1:37:02 informed consent here’s your risk to reward ratio and they’ve just reanalyzed
1:37:06 the data in the past few months and decided that they were wrong it was bad
1:37:10 data they shouldn’t have taken all these women off of hormones the amount of
1:37:16 dementia and cardiac disease and bone fractures and on and on and on that
1:37:21 happened because those women were starved of hormones is devastating to me
1:37:26 so it comes down to understanding the mechanism of action of how these things
1:37:30 work sharing that as best as you can with your patients and then having a
1:37:34 conversation and letting the patient decide so but in the case of the
1:37:37 micro dosing you’re going to tell me the upsides in that informed consensory
1:37:41 what would you tell me the downsides might be I would tell you the downsides
1:37:46 that we see in the data with the high doses okay but then you would extrapolate
1:37:51 from there that you would have those downsides meant but in smaller frequency
1:37:55 much much smaller potential but also you keep a sharp eye on your patient you
1:38:00 don’t just send somebody out with a prescription and say see ya good luck you
1:38:04 know it’s close monitoring you’re making sure to keep track of things we’re
1:38:07 running labs we’re checking in we’re making sure symptom pictures aren’t
1:38:12 showing up and it’s upside versus downside people are gonna listen to this
1:38:18 and they’re gonna think okay so I should be micro dosing as MPEC and what
1:38:22 might happen is people will go online and they’ll try and buy as MPEC and then
1:38:25 they’ll at home start I don’t know putting it in their tea or whatever oh
1:38:31 no that’s not a good idea I would I don’t know what the situation is in the
1:38:34 UK but I know in the United States we have longevity doctors we have smart
1:38:37 functional medicine doctors we have doctors that have access to compounding
1:38:41 pharmacies and I’m hearing at least in certain parts of Canada there are
1:38:46 compounding pharmacies I don’t know what the situation is in the UK I believe
1:38:51 there are compounding pharmacies are being driven out by big pharma because
1:38:54 they’re pretty punk rock they’re doing individualized medicine for patients
1:38:57 they create medications for a patient at the dose that’s tolerable for the
1:39:03 patient and I highly encourage folks to do their research and find a doctor
1:39:07 who’s willing to work with them and at the very least consider the starting
1:39:12 dose that is in the pre-filled pens and talk to your doctor about not
1:39:16 escalating so quickly and making sure that you implement the other lifestyle
1:39:21 factors aggressively so that you don’t have to increase the dosage and I’m
1:39:24 hearing from people in my program that are doing quite well that way they
1:39:26 don’t have access to compounding pharmacists they don’t even have access
1:39:30 to like a longevity doctor I understand that’s not available for everyone and
1:39:34 there’s there’s economic issues I get all that so they’re finding great
1:39:38 success in that 0.25 milligram and they’re being really diligent about all
1:39:42 the other lifestyle interventions and they’re doing awesome and so I don’t
1:39:46 know any doctor that would want to crank up a dose of any medication if a
1:39:50 patient came to me and said doc I want to start on this you know the standard is
1:39:53 this dose I want to start on this dose and I don’t want to go up I’d be like
1:39:56 hallelujah because anytime you increase the dose of anything you’re gonna get
1:39:59 side effects are you seeing the weight loss benefits in people that are
1:40:04 micro dosing if they’re metabolically optimized and or they really start
1:40:09 working on it so if somebody walks in and they’ve got 30 40 pounds to lose I
1:40:13 have seen them successfully micro dosing so long as they take that
1:40:18 opportunity to do all the things they cannot sit on their ass and eat junk
1:40:21 food all the things what are all the things so strength training a couple
1:40:24 times a week lifting something heavy that might just mean filling up water
1:40:27 jugs and picking them up and walking across your room it might mean picking
1:40:31 up your cat and doing some squats every night just starting to use the muscle and
1:40:37 why strength training because muscle is the currency of metabolic health like
1:40:43 we need muscle mass in order for ourselves to be optimally insulin
1:40:47 sensitive it’s just how it works we gobble up our blood sugar and we
1:40:51 regenerate our mitochondria predominantly in the muscle so we need
1:40:55 muscle it’s a very important organ system it’s not just a mover you know we
1:40:59 don’t just move our our bones around with it you’ve got to have got Dr. Gabriel
1:41:03 Lyonon and she’ll give you the whole muscle conversation but muscle is
1:41:07 absolutely non-negotiable and so strength training man woman I don’t care
1:41:11 what age they are it’s something we have to focus on it might be push-ups it
1:41:16 might be I saw some cool stuff around the parks around here you guys have you
1:41:20 it’s way better here than it is in the U.S. it’s like not even emphasized so my
1:41:24 husband’s like that’s like a setup thing and that you know it’s like some blocks
1:41:27 of wood with some metal on it but it was set up as a little exercise area in one
1:41:33 of the parks so making sure that’s dialed in prioritizing protein okay making
1:41:37 sure the food you choose to put in your mouth is nutritionally dense what’s the
1:41:45 bang for your buck is it brightly colored is it coming from a lab or coming
1:41:49 from a factory in a package with a hundred ingredients in it or is it a
1:41:53 whole food right is it is it food that came off the farm is it food that looks
1:41:56 like how God made it however you want to think of it simplistic so I’m gonna
1:42:01 start lifting weights I’m gonna I’m gonna start lifting weights and then I’m
1:42:06 gonna start eating lots of protein yes and what else we need to do make sure
1:42:10 that you eat a variety of colorful foods right so just just focus there I hate
1:42:13 taking foods away from people start there you’ll fill up and then you don’t
1:42:16 need the rest right you’re gonna get up and go for three walks a day like I
1:42:20 mentioned three ten minute walks and I think ideally morning because you’re
1:42:24 getting your morning sunlight go out at noon so you’re high noon light you’re
1:42:27 gonna do wonderful things for your leptin and for your circadian rhythm if
1:42:30 you hit the light at three times a day and then you’re gonna go for that late
1:42:33 afternoon walk so that might just be going out with your dog it might be going
1:42:37 out with a friend whatever might be going out at lunch break whatever just go
1:42:41 around the block these are these these sound very similar to your six pillars
1:42:44 for a pain-free life which you write about in your book pain-free and strong
1:42:48 yeah so we covered a few of them here we’ve covered the strength training one
1:42:53 and I had some really awesome stats that I found in one study 186 people with
1:42:57 tight two diabetes were split into three training programs one was one group with
1:43:01 strength training the next was moderate cardio training and the third is a
1:43:05 combination of both and the strength training only group lost the most fat
1:43:09 gain the most strength and lean body mass and had the biggest decrease in its
1:43:13 insulin resistance and that was in women’s health yes you know I think one
1:43:15 of the things that we’ve always assumed and I’ve certainly assumed it is that
1:43:18 as I get older I’m just gonna lose muscle and that’s just what it is yeah
1:43:24 it’s not true now it’s we even have studies showing that folks in their 70s
1:43:27 can maintain and build muscle even if we maintain it right even if we just
1:43:32 maintain it so it’s critical this is not negotiable I have a 24 year old
1:43:35 daughter who is starting to understand this that she’s starting to get it right
1:43:39 and she’s like okay mom what do I do and I’m like just pick up your dogs she’s
1:43:42 got two different dogs that are two different sizes I’m like just do squats
1:43:46 with your dogs start doing push-ups off the side of your couch you can do this
1:43:49 at home right there’s so many opportunities online now that everything’s
1:43:52 out there and it’s free you just have to actually put in the time we’ve covered
1:43:56 movement there we covered strength we’ve covered the food and gut the four
1:44:01 others you’ve got in this pillow one of them is sleep sleep so sleep can be
1:44:05 elusive for folks especially if they’ve got hormonal issues and/or they’ve got
1:44:09 insulin resistance and metabolic dysfunction which drives the hormonal
1:44:14 issues so it’s really important that you you have to prioritize your sleep but
1:44:18 you have to protect your sleep and when I say protect it I mean are you sleeping
1:44:21 with a husband who’s snoring all night long are you in a really noisy
1:44:25 environment you have to add earplugs in is it too bright in your room do you have
1:44:29 to put an eye mask on like what’s basically paging get the TV out of the
1:44:33 room the TV is not helping you the bedroom is for sex and sleep get the
1:44:38 husband out the room maybe well you know what people snore when they’re
1:44:41 metabolically on sound and they’re overweight too so if we can get the
1:44:45 husband involved in the activities then hopefully everybody gets better and the
1:44:48 snoring goes down so yes you’ll get a new husband I guess well yeah when I was
1:44:52 dating it was a big deal actually I was like I would ask them on the first day
1:44:55 how’s your sleep and if they said it was not good I’m like that’s not agreeable
1:45:00 to me I’m not messing with this so just really off to going to bed at the same
1:45:04 like be an adult be a grown-up we put our kids to bed at a normal time every day
1:45:07 we have a rhythm with them right they go to bed they get up the same time every
1:45:09 day we have to do that with adults stop sleeping with your phone by your head
1:45:13 stop sleeping with it in the room what about sleeping pills I don’t love
1:45:17 sleeping pills I have used them clinically I don’t love Ambien or any of
1:45:20 those types of drugs but there are other options to help people get to sleep we
1:45:25 can use herbs I think pretty well too but we have got to we’ve got to do what
1:45:29 we’ve got to do to reset the sleep but I’ll tell you number one if your sleep
1:45:33 is off and you’re not exercising every day I don’t even want to hear about it
1:45:36 because if you’re not exhausting your energy like you would your puppy or your
1:45:40 child of course you’re not going to be able to sleep and number two if your
1:45:43 circadian rhythm is screwed up if you’re not getting out that morning
1:45:46 sunlight is so huge if you’re not getting out in the daylight I know when
1:45:49 it’s gray in Oregon sometimes it’s gray all day long and I can’t even tell what
1:45:53 time of day it is and I will still go out there in a raincoat and make sure I’m
1:45:57 out in the daylight even though it’s gray as heck so that is absolutely
1:46:00 critical both of those things will help improve your sleep why did you include
1:46:05 mindset as one of your six because you have to believe that you’re going to
1:46:08 accomplish this that goes into the dopamine pathway it’s a challenge right
1:46:12 this is my challenge this is and I mean challenge in a good way I think of it
1:46:16 as a quest not as a negative challenge right I don’t want people to ever feel
1:46:21 like they’re up against an insurmountable wall I heard that a lot with COVID when
1:46:24 I was talking about weight loss and metabolic optimization people would say
1:46:28 I have too much weight to lose there’s no point there’s always a point we can
1:46:31 always start to decrease inflammation and improve metabolic health even if the
1:46:36 scale isn’t shifting it doesn’t matter so we really have to go into this with a
1:46:40 winner’s mindset we have to be goal-oriented I’m sure you could
1:46:43 actually chime in on that too like what are the things that you do that drive you
1:46:47 to get up and go do the things that you do that might be hard or challenging but
1:46:51 you know they are what you need to do to move the needle and that’s mindset it
1:46:54 has to start there if it doesn’t start there if you don’t make a decision a
1:46:59 concerted decision to execute you’re never going to get there that’s super
1:47:02 difficult isn’t it because people I’d say we all go with their own traumas and
1:47:05 their own complex psychological state that getting them to shift their
1:47:09 perspective on the world is like trying to convert a religious person to another
1:47:14 faith it is I think people are outcome oriented and I see the potential but
1:47:19 that’s where I said remember short-term long-term goals if I’m only focused on
1:47:22 the outcome I’m never going to get there and when I do that dopamine is going to
1:47:24 drop off and I’m going to be like well shit I’m gonna fly you know just fly
1:47:30 back to where I was it’s the short-term it’s the I want to win I want to feel
1:47:34 better I want a better life for myself I want a better life for my children I
1:47:36 want to bet I want to be a better person for the people around me maybe people
1:47:39 are single and they’re looking for someone I always get asked that how’d you
1:47:42 find a great guy I’m like you have to be a great person you have to make
1:47:45 yourself a great healthy person to attract another great healthy person so
1:47:49 it’s the journey it’s not the destination right that’s just health 101 it’s the
1:47:53 journey not the destination interestingly in your in your book you
1:47:59 don’t have a chapter about this but you’ve said in other situations that
1:48:04 saunas have been a pretty critical beneficial tool for you and your health
1:48:08 over the past couple of years yes on it just getting hot like you can get hot
1:48:12 in a bathtub you can get hot through exercise but just getting your body
1:48:15 heat up will induce heat shock proteins which does so many great things for your
1:48:20 brain and immediately makes people feel better people wonder often they go do
1:48:24 some aerobic exercise and they think it might be the endorphins from the run and
1:48:28 I’m like if you turn into a sweaty mess during that you got a whole bunch of
1:48:31 other benefits too right we’re moving lymph we’re moving blood it doesn’t sound
1:48:36 that sexy but those heat shock proteins are it they have a significantly
1:48:40 positive impact on our immune system somewhere around 40% reduction in
1:48:45 pneumonia when induced so like do all the things right just go get hot and when I
1:48:49 am out of sorts and my immune system’s flaring and I’m sort of at the end of my
1:48:53 wits and I don’t know what to do I just think I got to go cook the shit out of
1:48:59 myself I just got to go get hot and get sweaty and then generally the solution
1:49:03 comes to me or I have a better path ahead of me right the little bit of light
1:49:05 will come out ahead I’m like okay that’s the direction I have to go and so
1:49:09 sauna is a wonderful way to do it but I know that’s not available to everyone so
1:49:13 bathtubs just getting hot when you when I look back through your childhood and
1:49:19 your teenage years and I see all this pain you know there’s a lot of I thought a
1:49:22 lot of pain five years old you’re in hospital
1:49:28 nurses are forcing you down as you go through your teenage years you were in
1:49:32 a really dark place mentally you as you said you were suicidal and you tried to
1:49:37 overdose on medicine I think I was early I was talking to my husband about this
1:49:41 the other day I think I was a really early version of what we’re seeing with
1:49:44 so many young people today I think I was you know I was brought up on a lot of
1:49:48 ultra process foods as ultra process as they would have been in those days a lot
1:49:52 of Wonder Bread and Baloney and you know Bel Vita cheese I don’t know what you
1:49:59 have here but you know like a processed cheese blob and I think that my falling
1:50:02 apart of my health and my mental well-being in my teenage years was a
1:50:07 direct result of just severe malnutrition and ultra process food
1:50:12 addiction did you have ADHD as well yeah they called it hyperkinetic and you
1:50:16 know what the solution was they said get her a dog and make sure she’s always
1:50:21 physically active and keep her away from white foods so breads cookies crackers
1:50:25 processed foods right that was as processed as it got and I always think of
1:50:29 that old doctor and that advice because it was perfect it’s perfect whenever I
1:50:33 have a patient who’s really ailing I’m like you have a dog it’s really important
1:50:38 they have a dog there’s so many reasons but it’s it’s just simple stuff and I
1:50:41 think what we’re seeing now is a very extreme version of that and so many
1:50:45 young people are really really really suffering and my daughter was one of
1:50:51 them and she’s 24 and her friends are all so sick and have such health troubles
1:50:56 and it’s there’s no answers there’s only just more drugs their moms are sick their
1:51:00 moms all have autoimmune disease I mean it’s just devastating to me you know so
1:51:04 to me you say you know you mentioned like it’s hard when we’re in the soup of
1:51:09 toxins but to me it’s I’m put that’s my pushback that is how I push back against
1:51:15 the system I want to infect as many people as I can with the truth of their
1:51:18 responsibility of taking care of themselves the best way that they can
1:51:22 and you don’t have to do all of it all at once like I said it’s a journey so
1:51:27 just pick one thing like start with the walks or start with the milk jugs and
1:51:32 the push-ups or the squatting your cat I don’t care whatever it is but start with
1:51:35 one thing and then start to build and just start making these things habits
1:51:39 right just routine and have it routine and habit and to me they’re just non
1:51:44 negotiable it’s just the way it is and that’s the only way I I mean I’m bat
1:51:48 shit crazy if I don’t lift weights and I don’t eat well and I think a lot of
1:51:52 people are and I think we just medicate them or we dismiss them or we just sort
1:51:58 of allow them to sort of descend further into the misery we can live with
1:52:02 neurodivergence we can live with I mean I do think I have a bit of neurodivergence
1:52:05 as well or whatever they would have called it back then but I I think that
1:52:08 we can live with these things harmoniously and turn them into superpowers
1:52:13 so long as we take good care of ourselves I had a whole career built off of
1:52:17 helping people with chronic pain because I understood it because I had lived with
1:52:19 chronic pain my whole life right like I intimately understood how to help them
1:52:24 and I thought outside the box because I knew what it felt like and I just wanted
1:52:28 to help them and I think that that’s what it comes down to and you’re in your
1:52:32 early 30s but when you get to your late 40s and you start waking up and you’re
1:52:37 like oh so this is what you know what it feels like hopefully you’ll become more
1:52:40 proactive that’s when you really start getting into it and then you start
1:52:43 seeking out other options maybe you maybe you will need some bioidentical
1:52:46 hormone replacement then you know maybe you’ll you’ll have a different
1:52:50 perspective at that point a bit as you go and experience it because we all do
1:52:53 right we can be vehemently one way and I’m not saying you are but a lot of
1:52:58 people are really dogmatic and I’m like okay well like the people who really hate
1:53:02 on ozempic I’m like well it’s showing great promise with Alzheimer’s and
1:53:06 Parkinson’s I hope you never need it if you’re so vehemently against it that you
1:53:10 won’t even consider it you know I don’t mean you but just in general like be
1:53:16 open-minded and seek knowledge what is the most important thing that you have
1:53:19 to share that maybe we haven’t talked about is there anything that we’ve
1:53:24 missed I would honestly just say always seek knowledge always be learning
1:53:27 always be seeking knowledge always be open-minded to different things even if
1:53:31 you’ve taken a hard stance on something consider alternatives and when you hear
1:53:35 people telling the truth or it sounds like they’re telling the truth double
1:53:41 check them look up sources don’t just follow influencers don’t just follow
1:53:45 what someone says on Instagram or what someone says on a podcast go look it up
1:53:50 and learn more I often are plant I’m planting seeds for my audience often and
1:53:53 I will tell them something and they want all the information right then and I’m
1:53:57 like no no no I’m trying to get you to actually go look up more information I
1:54:01 want everyone in my audience to be a knowledge seeker because that is how
1:54:04 you learn and that is how you grow and that’s how you stay on top of it and
1:54:08 that’s how you stay one step ahead right I have a closing tradition on this
1:54:12 podcast as well where the last guest leaves a question for the next guest
1:54:15 not knowing who they’re gonna be leaving it for and the question left in the
1:54:23 driver’s here for you is see when you reach the end of your life what has
1:54:27 brought you the most joy and is that the thing you’re most proud of
1:54:36 yes I have picked a hard path for myself I I always try to be brave and tell the
1:54:41 truth as I know it and it’s not always popular and as my audience grows it
1:54:45 gets harder because I get more and more pushback but I refuse to step down when
1:54:50 I find something that can help people I have dedicated my life to trying to get
1:54:53 that message out to as many people as I can if it would be helpful to them and
1:55:00 so well at at times I’ve felt like what have I done why why do I keep doing I
1:55:04 feel like Joan of Arc at times you know I’m the girl over here with the early
1:55:08 unpopular opinion but I feel proud of that I know my daughter is proud of me
1:55:13 and I know that I’ve helped a lot of people a lot I know a lot of people have
1:55:16 and they’ve come back to me and said you saved my life in one way or another and
1:55:20 I’m really proud of that and that’s I just want to be a service as best I can
1:55:26 and my gift I think is taking complicated information and explaining it
1:55:30 simplistically so that people can implement and while that’s been hard
1:55:34 and challenging and I’ve received a ton of pushback that has aged me and made me
1:55:40 sick at times I’m really proud of that Dr. Tina Moore I find it so interesting
1:55:45 you know because um it’s an idea this idea of micro dosing as MPEC is not one
1:55:50 that I’ve come across before I discovered your work online and I’m of the
1:55:56 contingent where I like to hear new ideas that maybe haven’t had all the
1:56:03 clinical studies run on them before but I like to I like to imagine the
1:56:05 possibilities and then obviously there’s scientists that are going to do the
1:56:09 research and that research is going to continue for many decades to come but
1:56:13 I’m intrigued by it I’m curious by it doesn’t mean that I’m going to go on
1:56:16 Google and start micro dosing myself in my bedroom I’m absolutely not going to do
1:56:21 that but I like I like how it assembles a picture in my mind about this new thing
1:56:25 and the potential possibilities of this new thing so that’s why I wanted to
1:56:30 have a conversation today and I think as you’ve clearly said everybody listening
1:56:33 should do their own research they should go out there they should speak to
1:56:37 their doctor they should look at the studies that we’ve cited today they
1:56:40 should do their own independent research to form their own view but I think all
1:56:44 progress starts with these sort of initial hypotheses these sort of
1:56:50 anecdotal experiences and then society eventually catches up or society proves
1:56:54 that that hypothesis was something else or wrong in some way and that’s why I
1:56:58 have these conversations because I think it’s you know when I think handled in
1:57:02 the right way and when presented with the nuance of all these subjects they can
1:57:07 be the start of a snowball that can cause society to start asking questions
1:57:11 and through that debate and through that investigation we can hopefully arrive
1:57:14 at a better place and I especially like these conversations when I believe
1:57:17 that someone’s intent and their intentions are so pure and so well
1:57:20 intentioned and that’s certainly the case for you so thank you so much for the
1:57:24 work you’re doing and all the wonderful people you’ve helped I’ve seen so many
1:57:28 hundreds of comments from people that have benefited from the work that you
1:57:31 do and I think that’s a remarkable thing and a force for good in the world so
1:57:34 it’s been a pleasure to speak to you today and thank you for making the journey
1:57:38 despite the honey-aided disc. Thank you so much for having me, it’s a true
1:57:40 honor.
1:57:42 , thank you.
1:57:44 , thank you.
1:57:46 , thank you.
1:57:48 , thank you.
1:57:50 .
1:58:03 [Music]