What’s Your Problem?
In recent decades, medical research has fundamentally changed how we think about heart disease. This fresh understanding has opened up new ways to prevent heart attacks. Eric Topol is a cardiologist and the founder of the Scripps Research Translational Institute in San Diego. Eric’s problem is this: How can doctors use recent technological developments to do a better job at preventing heart attacks?
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How to Save the Most Lives
Farzad Mostashari is the co-founder and CEO of Aledade. Farzad’s problem is this: How can we pay doctors to keep us healthy, rather than treating us after we get sick? People have been struggling to…
From Story of the Week with Joel Stein: Billionaires Prepping for the Apocalypse
This bonus episode is from Story of the Week with Joel Stein, a new Pushkin podcast. On Story of the Week, journalist Joel Stein chooses an article that fascinates him, convinces the writer to tell…
The Investors Everybody Ignored
Sallie Krawcheck is the founder and CEO of Ellevest, an investment firm for women that has over $1 billion in assets under management. In her career in finance, Sallie was often one of the only…
Sam Bankman-Fried Revisited
In May of this year, we interviewed Sam Bankman-Fried, the young billionaire philanthropist who started the crypto exchange FTX. Last week, in a matter of a few days, FTX collapsed and filed for bankruptcy, and…
Machiavelli’s Tips for Getting Ahead at Work
Stacey Vanek Smith is the author of “Machiavelli for Women: Defend Your Worth, Grow Your Ambition, and Win the Workplace.” Her problem is this: How do women get ahead in a workplace that is stacked…
Google’s Journey to the Edge of Search
Cathy Edwards is vice president and GM of Search at Google. Cathy’s problem is this: how do you teach computers to tell people what they want to know, even if they don’t know how to…
Paying People to Turn Off the Fridge
Matt Duesterberg is co-founder and president of OhmConnect. Matt’s problem: How do you build a business around getting people to save energy? Not all that much. And not all the time. But just enough, at…
Turning Writers into Publishers
Chris Best is co-founder and CEO of Substack. Chris’s problem: How do you help writers make a living from a thousand true fans? Substack is a company that helps writers send subscription-based email newsletters. Which,…
Shopify: The Business That Helps Build Businesses
Harley Finkelstein is the president of Shopify. He may love entrepreneurship more than anyone we’ve ever met. Harley’s problem: How do you aggregate the power of millions of small businesses to help them compete against…
Putting Carbon Back Into the Ground
Shaun Kinetic is co-founder and chief scientist of Charm Industrial. Shaun’s problem: How do you put billions of tons of carbon back into the ground? Charm Industrial is fighting climate change in a giant but…