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  • Can the Plant Microbiome Revolutionize Farming?

    The invention of synthetic fertilizer was one of the key breakthroughs of the 20th century. It’s the reason we can grow enough food to feed billions of people. It’s also super energy intensive. Karsten Temme…


  • Turning Pollution into Jet Fuel

    Jennifer Holmgren is the CEO of LanzaTech. Her problem is this: How do you capture pollution from factories, feed it to bacteria, and get the bacteria to produce ethanol, which can become everything from polyester…


  • Reinventing Mining to Power the World

    Moving from fossil fuels to renewable energy will require huge amounts of copper, lithium, and other metals. Kurt House is the co-founder and CEO of KoBold Metals. The company recently made a huge copper discovery…


  • Inventing a Vaccine for Bees

    Dalial Freitak and Annette Kleiser are the co-founders of Dalan Animal Health, a company that has brought to market the first vaccine for insects. Their problem is this: How do you turn a discovery about…


  • A Better Way to Make the Chemicals in Everything

    Sean Hunt is the co-founder and CTO of Solugen, a company that sells around $100 million a year of industrial chemicals. Sean’s problem is this: How do you make the chemicals that go into everything…


  • How Refrigeration Changed the World

    Refrigeration is an underrated technology. It completely transformed what billions of people eat every day.  Today’s guest, Nicola Twilley, tells the story of refrigeration in her new book, Frostbite: How Refrigeration Changed Our Food, Our…


  • Detecting Deepfakes With AI

    As generative AI tools improve, it is becoming easier to digitally manipulate content and harder to tell when it has been tampered with. Today we are talking to someone on the front lines of this…


  • Turning Old Cans Into Clean Energy

    Aluminum is the most abundant metal in the Earth’s crust. It’s cheap, ubiquitous, and surprisingly energy dense. Peter Godart is the co-founder and CEO of Found Energy. Peter’s problem is this: How can you use…


  • Moneyball, Soccer, and the Gap Between Analytics and the Real World

    Sarah Rudd is the co-founder and CEO of the soccer analytics company src | ftbl (It’s pronounced “Source Football.”) Sarah’s problem is this: How do you model a sport as fluid and complex as soccer…


  • Using Computer Vision to See What Coaches Can’t

    Jimmy Buffi is the CEO and co-founder of Reboot Motion, which uses biomechanics to help athletes in Major League Baseball and the NBA. Jimmy’s problem is this: How do you turn data about how professional…


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