What’s Your Problem?
Mike Blue is the CEO of HistoSonics. The company recently developed a device that uses ultrasound to destroy tumors.
On today’s show, Mike talks about how a garage-built prototype became an FDA-approved machine; changing the company’s story after a failed clinical trial; and why he loves being a salesman but hates most sales pitches.
See omnystudio.com/listener for privacy information.
Using Gene Therapy to Help the Blind See
After decades of research, gene therapy is starting to work. Shannon Boye is a professor of cellular and molecular therapeutics at the University of Florida. She is also the co-founder and chief scientific officer of…
Using Gene Therapy to Help the Blind See
After decades of research, gene therapy is starting to work. Shannon Boye is a professor of cellular and molecular therapeutics at the University of Florida. She is also the co-founder and chief scientific officer of…
Bringing Back Mammoths and Dodos*
*Or at least, sort of bringing back mammoths and dodos. Beth Shapiro is the chief scientific officer at Colossal Biosciences and the author of How to Clone a Mammoth: The Science of De-Extinction. Beth’s problem…
What Elevators Teach Us About Technology, Design, and Human Behavior
The elevator made the modern city possible: No elevators, no skyscrapers. Today, people are working on entirely new kinds of elevators that can go higher and faster than ever. On today’s show, we talk about…
Can the Plant Microbiome Revolutionize Farming?
The invention of synthetic fertilizer was one of the key breakthroughs of the 20th century. It’s the reason we can grow enough food to feed billions of people. It’s also super energy intensive. Karsten Temme…
Turning Pollution into Jet Fuel
Jennifer Holmgren is the CEO of LanzaTech. Her problem is this: How do you capture pollution from factories, feed it to bacteria, and get the bacteria to produce ethanol, which can become everything from polyester…
Reinventing Mining to Power the World
Moving from fossil fuels to renewable energy will require huge amounts of copper, lithium, and other metals. Kurt House is the co-founder and CEO of KoBold Metals. The company recently made a huge copper discovery…
Inventing a Vaccine for Bees
Dalial Freitak and Annette Kleiser are the co-founders of Dalan Animal Health, a company that has brought to market the first vaccine for insects. Their problem is this: How do you turn a discovery about…
A Better Way to Make the Chemicals in Everything
Sean Hunt is the co-founder and CTO of Solugen, a company that sells around $100 million a year of industrial chemicals. Sean’s problem is this: How do you make the chemicals that go into everything…
How Refrigeration Changed the World
Refrigeration is an underrated technology. It completely transformed what billions of people eat every day. Today’s guest, Nicola Twilley, tells the story of refrigeration in her new book, Frostbite: How Refrigeration Changed Our Food, Our…