a16z Podcast

  • Columbia CS Professor: Why LLMs Can’t Discover New Science

    From GPT-1 to GPT-5, LLMs have made tremendous progress in modeling human language. But can they go beyond that to make new discoveries and move the needle on scientific progress? We sat down with distinguished…


  • Monitoring the Situation #3: Who Is Nick Land?

    Zach Dell is founder and CEO of Base Power, an energy tech company that builds affordable, reliable power via home batteries. In this episode of Monitoring the Situation, a16z General Partners Erik Torenberg, Katherine Boyle,…


  • Sam Altman on Sora, Energy, and Building an AI Empire

    Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later. In this episode, a16z Cofounder Ben Horowitz and General…


  • How to Build a Real Estate Marketplace – Kaz Nejatian, Opendoor CEO

    Opendoor is trying to make it easier to buy a home. Kaz Nejatian just joined as CEO to help them succeed. In this episode, a16z General Partners Alex Rampell and Erik Torenberg sit down with…


  • Can the US Beat China’s Engineering State?

    From high-speed rail to electric cars to batteries to AI, it’s clear that China can operate with incredible speed at massive scale. Can the US still compete? We sat down with Dan Wang, a Research…


  • Monitoring the Situation #2: Alana Newhouse

    Two trends in media have been abundantly clear since 2020: legacy media is dying, and independent media is rising. a16z General Partners Erik Torenberg and Katherine Boyle sit down with Tablet founder and editor-in-chief Alana…


  • Software is Eating Labor

    Software has fundamentally changed the way we record, store, and share information. Its next act is to fundamentally change the nature of our economy, capturing trillions of dollars of value in the process. In this…


  • The Ben & Marc Show: China Has Scale. Can America Catch Up?

    Ben, Marc, and Erik Torenberg are joined by Brian Schimpf, Co-Founder & CEO of Anduril, and Chris Power, Founder & CEO of Hadrian. Together, they dig into America’s defense production gap: why the U.S. can…


  • Cheeky Pint: Marc Andreessen, John Collison & Charlie Songhurst on Tech’s Big Questions

    Today we’re sharing a feed drop from Cheeky Pint, where Stripe cofounder and president John Collison chats with legends in technology over a pint of Guinness. In this episode, John is joined by a16z cofounder…


  • Building an AI Physicist: ChatGPT Co-Creator’s Next Venture

    Scaling laws took us from GPT-1 to GPT-5 Pro. But in order to crack physics, we’ll need a different approach.  In this episode, a16z General Partner Anjney Midha talks to Liam Fedus, former VP of…


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