a16z Podcast

  • The Critical Technology in Finding Critical Materials

    Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy transition have come to a height in recent years. In this episode, a16z…


  • DeepSeek: America’s Sputnik Moment for AI?

    Two words have caught the Internet by storm. DeepSeek.  The Chinese reasoning model r1 is rivaling others at the frontier with an open-source MIT license, methods that some claim may be 45x more efficient, an…


  • Ben Horowitz Sharing History with Dr. Clarence Jones, MLK’s Speechwriter

    This week, a16z cofounder Ben Horowitz had a rare and invaluable conversation with Dr. Clarence B. Jones, a pivotal figure in American history.  Dr. Jones, who served as speechwriter, attorney, and advisor to Dr. Martin…


  • How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril

    How is AI reshaping modern warfare?  Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sorting through the enormous amount…


  • RIP to RPA: How AI Makes Operations Work

    Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’t handle. In this episode, a16z partner Kimberly Tan discusses the shift from rigid RPA systems to AI-powered agents…


  • Marc Andreessen: Can Tech Finally Fix Healthcare?

    Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why…


  • Building Substack: Reinventing Media Through the Inbox

    Email, a technology from 1971, is powering one of today’s most disruptive media platforms. In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution…


  • Crypto Trends for 2025: Stablecoins, App Stores, UX, and More

    with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes — which also look ahead to 2025 —  covering our annual Big Ideas lists, where various a16z crypto team members…


  • Super Staffing Healthcare, Codifying Compliance, & Scaling Services

    As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways.  In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into…


  • The Race for AI—Search, National Infrastructure, & On-Device AI

    The AI race is on, and 2025 could be its most transformative year yet. In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI…