a16z Podcast

  • Ben Horowitz on the Next Technology Era

    David Ulevitch speaks with Ben Horowitz about what it means to lead the technology industry at scale, and the responsibilities that come with it. Following the firm’s largest-ever fundraise, they discuss how venture capital, technology,…


  • Crypto Fund 5: We Raised $2.2B. Here’s Why.

    Robert Hackett speaks with the general partners at a16z crypto about the launch of their fifth crypto fund and the current state of the industry. They reflect on how crypto has evolved from an ideological…


  • The New Space Race: NASA, Artemis, and the Race to the Moon

    Morgan Brennan speaks with NASA Administrator Jared Isaacman about the next phase of American space exploration and the urgency behind returning to the moon. They discuss the Artemis program, the challenges of cost, speed, and…


  • Building Blackstone, Backing Costco, with Tony James

    David Haber speaks with Tony James about building enduring firms across multiple eras of finance. From joining DLJ when it was a subscale firm to helping grow Blackstone into one of the largest asset managers…


  • Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies

    Katherine Boyle speaks with Sarah Rogers, Under Secretary for Public Diplomacy, about the intersection of AI, free speech, and global information systems. They discuss how major technological shifts, from the printing press to the internet…


  • Balaji and Taylor Lorenz on AI and Media

    Theo Jaffee speaks with Balaji Srinivasan and Taylor Lorenz about how AI is reshaping media, trust, and online communication. Building on prior public disagreements between the two, the conversation revisits core tensions around media, technology,…


  • Workday’s Last Workday? AI and the Future of Enterprise Software

    Elena Burger speaks with Joe Schmidt, partner on the enterprise team at a16z, about the future of enterprise software in the age of AI. Using Workday as a case study, they discuss why many of…


  • The Shift in Global Drug Development

    Theo Jaffee and Gabriel Dickinson speak with Cremieux about China’s rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China’s progress, the surge in novel drug development,…


  • John and Patrick Collison on Stripe’s Growth, Agent Commerce, and the Future of Software

    This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe’s 34% growth and new employee tender offer, how agent commerce and stablecoins may require high-throughput blockchains built for millions…


  • Ben Horowitz on Venture Capital and AI

    Anjney Midha, founder of AMP PBC, speaks with Ben Horowitz, cofounder of a16z, about how venture capital changed from a small, relationship-driven business into a scalable system for backing new technology companies. They discuss network…


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