a16z Podcast

  • Journal Club: Slaying the Sleeper Cells of Aging with CAR T

    CAR T therapy is a groundbreaking medicine that uses engineered T cells to attack cancer. But CAR T cells (that is, chimeric antigen receptor T cells) can be programmed to recognize a huge range of…

  • Working, Making, Creating in Public… and Private

    We’re living in an unprecedented era of online collaboration, coordination, and creation. All kinds of people are coming together — whether in an open source project or company, an R&D initiative, a department in a…

  • GPT-3: What’s Hype, What’s Real on the Latest in AI

    In this episode — cross posted from our 16 Minutes show feed — we cover all the buzz around GPT-3, the pre-trained machine learning model from OpenAI that’s optimized to do a variety of natural-language…

  • Taking the Pulse on Medical Device Security

    Many don’t realize we even need to think about the possibility of security hacks when it comes to things like pacemakers, insulin pumps, and more. But when bits and bytes meet flesh and blood, security…

  • Journal Club: A New Path to Antibiotic Resistance

    Ever since the discovery of antibiotics, microbiologists have worried about and studied how bacteria acquire resistance to these drugs. Adding to the complexity of this problem is the fact that it is not always clear…

  • Cybercrime, Incorporated

    A dive into the sociological, operational, and tactical realities of this murky underworld, Lusthaus and de la Garza discuss who the players are, what they are motivated by, and specialize in—as well as how basic…

  • How Transparent Pricing Drives Healthcare Change

    Dr. Marty Makary—surgical oncologist at Johns Hopkins University School of Medicine, and health policy and innovation expert—has long been a passionate advocate for transparent pricing in the healthcare system. We don’t talk enough (or really…

  • Preserving Digital History: How to Close the Web’s ‘Memory Hole’

    More than 98% of the information on the web is lost within 20 years, and huge gaps exist in our digital and cultural history. Zoran Basich and Alex Pruden of a16z talk to Brewster Kahle…

  • Alex Honnold on Human Performance (part 2) – Climbing and Entrepreneurship

    In part 1 of our series on human performance, we looked at the limits of human potential in climbing and other sports – and how we push those limits through technology and training. In this…

  • Alex Honnold on Human Performance (part 1) – Where’s the Limit?

    Is there a limit to what humans can do? And if so, how do you know when you’ve reached it? Welcome to part one of a two-part series on human performance with professional rock climber…

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