Huberman Lab
In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University.
We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and lifestyle strategies for improving gut health.
Episode show notes: https://go.hubermanlab.com/VXfckJf
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
Joovv: https://joovv.com/huberman
Function: https://functionhealth.com/huberman
Timestamps
00:00:00 Justin Sonnenburg
00:00:20 What is the Microbiome?
00:02:55 Microbiome Origin, Babies, Environmental Factors
00:04:47 Healthy Microbiome, Individuality; Industrialized vs Traditional Populations
00:07:06 Sponsor: AG1
00:08:30 “Reprogramming” the Gut Microbiome; Antibiotics, Western Diet
00:12:58 Cleanses & Fasting
00:13:55 Processed Foods & Microbiome, Artificial Sweeteners, Emulsifiers
00:17:35 Sponsor: Joovv
00:18:55 Inflammatory Western Diseases, Microbiome & Immune System
00:21:51 Fiber, Fermented Foods & Microbiome, Tool: Fermented Food Consumption
00:28:20 Sponsor: Function
00:30:00 Fiber, Depleted Microbiome, Industrialization, Sanitation
00:31:33 Antibiotics, Over-Sanitation, Disease, Hand Washing
00:33:26 Probiotics, Tool: Product Validation,
00:35:15 Prebiotics, Tool: Plant Consumption
00:37:48 Good Gut Book, Justin’s Research
Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
My guest is David Anderson, PhD, a world expert in the science of sexual behavior, violent aggression, fear and other motivated states. Dr. Anderson is a Professor of Biology at the California Institute of Technology…
Focus Toolkit: Tools to Improve Your Focus & Concentration
In this episode, I provide a list of behavioral, nutritional, and supplement-based tools you can use to improve your ability to get into a focused state to do mental or physical work. I explain science-supported…
LIVE EVENT Q&A: Dr. Andrew Huberman at the Newmark Theatre in Portland
Recently I had the pleasure of hosting two live events, one in Seattle, WA and one in Portland, OR. These events were part of a lecture series called The Brain Body Contract. My favorite part…
Dr. Erich Jarvis: The Neuroscience of Speech, Language & Music
My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis’ research spans…
What Alcohol Does to Your Body, Brain & Health
In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to…
LIVE EVENT Q&A: Dr. Andrew Huberman at the Moore Theatre in Seattle
Recently I had the pleasure of hosting two live events, one in Seattle, WA and one in Portland, OR. These events were part of a lecture series called The Brain Body Contract. My favorite part…
Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast…
Sleep Toolkit: Tools for Optimizing Sleep & Sleep-Wake Timing
In this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on…
Dr. Emily Balcetis: Tools for Setting & Achieving Goals
My guest this episode is Dr. Emily Balcetis, PhD, Professor of Psychology at New York University (NYU). Dr. Balcetis’ research focuses on how our perception of the world, particularly our visual perceptions, influences our level…
The Science & Treatment of Bipolar Disorder
In this episode, I explain the biology, symptoms, causes and types of bipolar disorder (sometimes called bipolar depression). I discuss neuroplasticity and how the brain normally regulates mood, energy, and perceptions; then, I contrast that…