Huberman Lab
Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don’t just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy’ with cellular energy and provides science-supported tools to improve your physical and mental health.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
Helix: https://helixsleep.com/huberman
Lingo: https://hellolingo.com/huberman
Function: https://functionhealth.com/huberman
Waking Up: https://wakingup.com/huberman
Timestamps
(00:00:00) Martin Picard
(00:03:50) What is Energy?, Energy Flow & Transformation
(00:07:53) Energy, Vitality, Emotions, Sensory Perception
(00:14:18) Sponsors: Helix Sleep & Lingo
(00:17:19) “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns
(00:25:26) Organelles, Mitochondria & Energy Transformation; Maternal Genes
(00:31:12) Mitotypes & Differentiation, Mitochondria as “Social Organisms”
(00:36:52) Food & Dysfunctional Energy Transformation
(00:40:02) Lifestyle Choices & Interests, Physiological Growth
(00:46:39) Pregnancy, Amenorrhea; Illness & Tiredness
(00:51:07) Sponsor: AG1
(00:52:29) Energy Transformation & Distribution; Body’s Wisdom, Feeling Sick
(00:56:27) Tool: Feel Your Energy; Breath & Energy
(01:02:31) Flow of Energy; Trade-Offs, Life Purpose & Enjoyment
(01:10:15) Biology, Meaningful Experiences & Energy Flow
(01:16:27) Sponsor: Function
(00:18:15) Inflammation, Energetic Flow
(01:20:43) Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging
(01:28:56) Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants
(01:37:06) Energetic Stress Signals, GDF-15, Cancer, Heart Failure
(01:42:18) Genes, Lifestyle & Aging
(01:47:54) Gray Hair Reversal, Stress; Inflammation & Aging
(01:57:37) Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation
(02:05:16) Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep
(02:10:58) Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto
(02:20:14) Alcohol & Energy Budget; Stress
(02:25:02) Exercise, Increase Mitochondria, Overtraining; Resistance & Growth
(02:33:06) Sponsor: Waking Up
(02:34:41) Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue
(02:41:31) Energy Flow & Experiences, Balance
(02:49:13) Transform Through Resistance, Energetic Awareness, Connection
(02:56:05) Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria
(03:01:02) Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation
(03:06:10) Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields
(03:12:16) Acknowledgements
(03:14:15) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter
Learn more about your ad choices. Visit megaphone.fm/adchoices

Nutrients For Brain Health & Performance
This episode I describe science-supported nutrients for brain and performance (cognition) and for nervous system health generally. I describe 10 tools for this purpose, including specific amounts and sources for Omega-3 fatty acids which make…
Effects of Fasting & Time Restricted Eating on Fat Loss & Health
This episode I discuss the science and practice of fasting also called time-restricted feeding. I review the data on how limiting food intake to specific portions of every 24-hour cycle (or fasting longer) impacts weight…
Dr. Craig Heller: Using Temperature To Optimize Performance, Brain & Body Health
This episode I am joined by Dr. Craig Heller, Professor of Biology at Stanford University and world expert on the science of temperature regulation. We discuss how the body and brain maintain temperature under different…
Controlling Your Dopamine For Motivation, Focus & Satisfaction
This episode serves as a sort of “Dopamine Masterclass”. I discuss the immensely powerful chemical that we all make in our brain and body: dopamine. I describe what it does and the neural circuits involved.…
Dr. Matthew Johnson: Psychedelics for Treating Mental Disorders
This episode I discuss medical research on psychedelic compounds with Dr. Matthew Johnson, Professor of Psychiatry and Behavioral Sciences at Johns Hopkins School of Medicine. We discuss the biology and medical clinical-trial uses of psilocybin,…
ADHD & How Anyone Can Improve Their Focus
In this episode, I discuss ADHD (Attention-Deficit Hyperactivity Disorder): what it is, the common myths, and the biology and psychology of ADHD. I discuss both behavioral and pharmacologic treatments for ADHD, and brain-machine interface tools.…
Healthy Eating & Eating Disorders – Anorexia, Bulimia, Binging
In this episode, I discuss what drives hunger and satiety, and the role our brain, stomach, fat and hormones play in regulating hunger and turning off the desire to eat more. I also address how…
Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will
In this episode, I interview Dr. Robert Sapolsky, Ph.D., Professor of Biology, Neurology & Neurosurgery at Stanford University. We discuss stress, what defines short-term versus long-term stress, and how stress can be beneficial or detrimental,…
Understanding & Conquering Depression
This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical…
Dr. Anna Lembke: Understanding & Treating Addiction
This episode I interview Dr. Anna Lembke, M.D., Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. Dr. Lembke is a psychiatrist expert in treating addictions of all kinds:…