Jared Baeten is senior vice president in virology at Gilead Sciences. Jared’s problem is this: In a world without a vaccine, how do you make a medicine that people will actually take to help prevent HIV?
There’s already a daily pill that reduces the risk of getting HIV, but a majority of people who are at high risk are unwilling or unable to take it.
So Jared and his colleagues are developing a new drug, lenacapivir, designed to be given as a shot once every six months.
Note: The views and opinions expressed in this episode are those of the guest and do not necessarily reflect the views or positions of any entities they represent.
Get early, ad-free access to episodes of What’s Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin shows.
Subscribe on Apple: apple.co/pushkin
Subscribe on Pushkin: pushkin.com/plus
See omnystudio.com/listener for privacy information.

Selling Billions of Crickets a Year
Mohammed Ashour is the co-founder and CEO of Aspire Food Group. The company just built the biggest cricket factory in the history of the world. His problem: How do you sell billions of bugs a…
From Patented: Inventing the Wheeled Suitcase
We put man on the moon before we invented the wheeled suitcase. Why did it take so long? Find out in this episode of Patented: History of Inventions, where host Dallas Campbell is joined by expert…
How the Nerds Conquered the NBA
Rajiv Maheswaran is the co-founder and president of Second Spectrum. Rajiv and his company figured out how to turn raw sports data into useful information for coaches. Today, the company works with basketball and soccer…
The Trick to Flying Cheap
David Neeleman has founded five airlines, including JetBlue. He recently launched a new airline, called Breeze. His problem: How do you use technology to bring down the cost of airfares? He’s been working on that…
Beer Without the Buzz
Bill Shufelt is the founder and CEO of Athletic Brewing Company. His problem: How do you turn non-alcoholic beer from a punchline into something people drink all the time? If you’d like to keep up…
John Green Tests the Limits of YouTube
John Green is the author of The Fault in Our Stars and six other novels. He also co-founded a company that makes educational videos that have been viewed billions of times. John’s problem: How do…
Taking Bets on the Future
Luana Lopes Lara is the co-founder of Kalshi, an exchange that lets ordinary people bet on everything from the path of inflation to what bills Congress will pass by the end of the year. Her…
From Unsung Science with David Pogue: The Man Who Stopped the Spammers
A special preview of the podcast, Unsung Science with David Pogue from CBS News. Journalist and author David Pogue finds the untold creation stories behind the most mind-blowing advances in science and tech—and hears from the characters…
Building Bespoke Weather Forecasts
Shimon Elkabetz is the founder and CEO of Tomorrow.io. His problem: How do you build a weather forecasting company from scratch? The company already sells weather intelligence to companies like JetBlue, Uber and the NFL. …
Squeezing the Entire Internet Into a Shoebox
Emily Leproust is the co-founder and CEO of Twist Bioscience. Her problem: How do you store data in DNA — and make it cheap enough to work in the real world. The cells in our…