a16z Podcast

  • Food, Drugs, and Tech—100 Years of Public Health

    The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a time of enormous upheaval and change, and rapidly…


  • On Pharma Trends and Big Company Innovation

    How does the world’s largest producer of medicines in terms of volume balance the science and the business of innovation? How does an enterprise at such vast scale make decisions about what to build vs.…


  • Personal Genomics: Where Are We, Really?

    This is a turn of the decade (and January-themed) look backward/ look forward into personal genomics, given recent and past retrospective and prospective pieces in the media on the promise, and perils, of the ability…


  • Why We Should Be Optimistic About the Future

    Many skeptics thought the internet would never reach mass adoption, but today it’s shaping global culture, is integral to our lives — and it’s just the beginning.  In this conversation from our 2019 innovation summit,…


  • What to Know about CFIUS

    When innovation and capital go global, so do restrictions on trade, foreign investment, and more. Over the past couple years, U.S. policymakers have expanded the scope of the Committee on Foreign Investment in the U.S.…


  • Are ISAs the Solution to Student Debt?

    A bold proposal: You go to college for free, then pay back the school after graduation—but only if you get a job in your field of study and make a high enough salary to afford…


  • Shonda Rhimes on How to Create Stories (and Products) People Want

    Hollywood and Silicon Valley seem so different, but are more alike than we think. What challenges do tech startup founders and other creative founders — like showrunners and executive producers — similarly face? Both have…


  • The Journey from 0 to 1, from Mosaic to Netscape

    As part of a new series where we will share select a16z partner appearances on other podcasts with our audience here, this episode is cross-posted from the new show Starting Greatness — featuring interviews with…


  • Direct Listings, Myths and Facts

    We’ve covered a lot of the strategic financing milestones for startups seeking to build a sustainable and enduring business — from mindsets for startup fundraising to when and how to build a finance functionwith a…


  • The Stories and Code of Culture Change

    There are some common tropes that can kill your company culture — whether it’s that corporate values can be weaponized; “fake it til you make it”; the “reality distortion fields” of visionaries vs. liars; and…


Let's Evolve Together
Logo