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In loving memory of Nolan Williams (1982-2025): ⁠https://stan.md/3Qle2zp⁠

In this Huberman Lab Essentials episode, my guest is Dr. Nolan Williams, MD, a triple board-certified psychiatrist and neurologist. We discuss cutting-edge treatments for depression and post-traumatic stress disorder (PTSD), including transcranial magnetic stimulation, neuromodulation, and psychedelic-assisted therapies. We also discuss the neurobiology and therapeutic potential of specific psychedelic compounds, including psilocybin, MDMA, ibogaine, and ayahuasca.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Function: https://functionhealth.com/huberman

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Timestamps

(00:00:00) Nolan Williams

(00:00:21) Depression

(00:02:45) Heart & Mind Connection, Transcranial Magnetic Stimulation (TMS)

(00:05:15) TMS for Depression

(00:07:47) Sponsor: Function

(00:09:24) SSRIs & Chemical imbalance, TMS, Psychedelics

(00:15:24) Psilocybin, MDMA, Trauma

(00:18:21) MDMA Clinical Trials & PTSD; Psilocybin & Depression

(00:20:18) Sponsor: BetterHelp

(00:21:38) Psilocybin, Brain Connectivity & Depression

(00:23:59) Ibogaine, Empathy; Psychedelic Breakthrough & Risk

(00:30:36) Ayahuasca, Behavior Change, Prisoners

(00:34:46) Sponsor: AG1

(00:36:05) Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT)

(00:40:07) Acknowledgements

Disclaimer & Disclosures

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